| Literature DB >> 7365750 |
A M Crider, T M Kolczynski, K M Yates.
Abstract
Nitrosourea derivatives 9--13 which utilize phensuximide (1) as the carrier were synthesized as potential central nervous system antitumor agents. The N-(2-chloroethyl)-N-nitrosourea 13 was active in the mouse ependymoblastoma brain-tumor system, as well as the intraperitoneal L1210 leukemia system.Entities:
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Year: 1980 PMID： 7365750 DOI： 10.1021/jm00177a024
Source DB: PubMed Journal: J Med Chem ISSN： 0022-2623 Impact factor: 7.446