Literature DB >> 7365739

5-substituted 2-amino-6-phenyl-4(3H)-pyrimidinones. Antiviral- and interferon-inducing agents.

W Wierenga, H I Skulnick, D A Stringfellow, S D Weed, H E Renis, E E Eidson.   

Abstract

Entities:  

Mesh：

Substances：

Year:  1980        PMID： 7365739     DOI： 10.1021/jm00177a004

Source DB:  PubMed          Journal:  J Med Chem        ISSN： 0022-2623            Impact factor:   7.446


× No keyword cloud information.
  10 in total

1.  The antitumour activity of the interferon inducer bropirimine is partially mediated by endogenous tumour necrosis factor alpha.

Authors:  M Scheringa; J N IJzermans; J Jeekel; R L Marquet
Journal:  Cancer Immunol Immunother       Date:  1990       Impact factor: 6.968

2.  Structure-activity relationships in human toll-like receptor 7-active imidazoquinoline analogues.

Authors:  Nikunj M Shukla; Subbalakshmi S Malladi; Cole A Mutz; Rajalakshmi Balakrishna; Sunil A David
Journal:  J Med Chem       Date:  2010-06-10       Impact factor: 7.446

3.  Effect of pyrimidinone treatment on lethal and immunosuppressive murine cytomegalovirus infection.

Authors:  R J Brideau; J A Wolcott
Journal:  Antimicrob Agents Chemother       Date:  1985-10       Impact factor: 5.191

4.  Synergistic antitumor activity of cyclophosphamide and ABPP in the treatment of established and advanced tumors in murine tumor models.

Authors:  A M Eggermont; P H Sugarbaker; R L Marquet; J Jeekel
Journal:  Cancer Immunol Immunother       Date:  1987       Impact factor: 6.968

5.  Toll-like receptor-8 agonistic activities in C2, C4, and C8 modified thiazolo[4,5-c]quinolines.

Authors:  Hari Prasad Kokatla; Euna Yoo; Deepak B Salunke; Diptesh Sil; Cameron F Ng; Rajalakshmi Balakrishna; Subbalakshmi S Malladi; Lauren M Fox; Sunil A David
Journal:  Org Biomol Chem       Date:  2013-02-21       Impact factor: 3.876

6.  Antitumor effects of oral administration of an interferon-inducing pyrimidinone, Bropirimine, on murine renal-cell carcinoma.

Authors:  T Fujioka; K Ishikura; M Hasegawa; K Ogyu; Y Matsushita; M Sato; F Sato; H Aoki; T Kubo
Journal:  Cancer Chemother Pharmacol       Date:  1995       Impact factor: 3.333

7.  Stimulation of innate immune cells by light-activated TLR7/8 agonists.

Authors:  Keun Ah Ryu; Lalisa Stutts; Janine K Tom; Rock J Mancini; Aaron P Esser-Kahn
Journal:  J Am Chem Soc       Date:  2014-07-28       Impact factor: 15.419

Review 8.  Structural evolution of toll-like receptor 7/8 agonists from imidazoquinolines to imidazoles.

Authors:  Deepender Kaushik; Arshpreet Kaur; Nikolai Petrovsky; Deepak B Salunke
Journal:  RSC Med Chem       Date:  2021-05-14

9.  Sensitivity of locally recurrent rat mammary tumour cell lines to syngeneic polymorphonuclear cell, macrophage and natural killer cell cytolysis.

Authors:  P A Aeed; D R Welch
Journal:  Br J Cancer       Date:  1988-12       Impact factor: 7.640

10.  Regioselective synthesis of 6-substituted-2-amino-5-bromo-4(3H)-pyrimidinones and evaluation of their antiviral activity.

Authors:  Kamaljit Singh; Kawaljit Singh; Jan Balzarini
Journal:  Eur J Med Chem       Date:  2013-07-05       Impact factor: 6.514
  10 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.