Literature DB >> 73643

Mitochondrial calcium overload: A general mechanism for cell-necrosis in muscle diseases.

K Wrogemann, S D Pena.   

Abstract

It is suggested that the mechanism of muscle-cell necrosis in various muscle diseases is explained by an increased net influx of calcium into cells which triggers a "vicious cycle" of mitochondrial calcium overloading and energy depletion. If correct, this hypothesis may offer the basis of a more rational treatment of some muscle diseases even before their primary aetiology is known.

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Year:  1976        PMID： 73643     DOI： 10.1016/s0140-6736(76)92781-1

Source DB:  PubMed          Journal:  Lancet        ISSN： 0140-6736            Impact factor:   79.321


  85 in total

1.  Acid hydrolase activity in red and white skeletal muscle of mice during a two-week period following exhausting exercise.

Authors:  V Vihko; A Salminen; J Rantamäki
Journal:  Pflugers Arch       Date:  1978-12-28       Impact factor: 3.657

Review 2.  Exercise-induced muscle damage and adaptation.

Authors:  C B Ebbeling; P M Clarkson
Journal:  Sports Med       Date:  1989-04       Impact factor: 11.136

3.  Exercise over-stress and maximal muscle oxidative metabolism: a 31P magnetic resonance spectroscopy case report.

Authors:  B R Newcomer; B Sirikul; G R Hunter; E Larson-Meyer; M Bamman
Journal:  Br J Sports Med       Date:  2005-05       Impact factor: 13.800

4.  Calcium action potentials in innervated and denervated rat muscle fibres.

Authors:  O Delbono; B A Kotsias
Journal:  Pflugers Arch       Date:  1991-04       Impact factor: 3.657

5.  Sites and mechanisms of localization of technetium-99m phosphorus radiopharmaceuticals in acute myocardial infarcts and other tissues.

Authors:  L M Buja; A J Tofe; P V Kulkarni; A Mukherjee; R W Parkey; M D Francis; F J Bonte; J T Willerson
Journal:  J Clin Invest       Date:  1977-09       Impact factor: 14.808

Review 6.  Mechanisms of exercise-induced muscle fibre injury.

Authors:  R B Armstrong; G L Warren; J A Warren
Journal:  Sports Med       Date:  1991-09       Impact factor: 11.136

7.  Thermoregulation and the role of calcium signalling in neurotransmission.

Authors:  Atmaram Yarlagadda; Anita H Clayton
Journal:  Psychiatry (Edgmont)       Date:  2008-12

8.  Incorporation of amino acids into soluble and membrane protein fractions of dystrophic hamsters.

Authors:  D M Nicholls; R C Creasy; M W Chin-See; J A Carlisle; A B Lange; M Saleem
Journal:  Biochem J       Date:  1980-08-15       Impact factor: 3.857

Review 9.  Adverse effects of drugs on muscle.

Authors:  F L Mastaglia
Journal:  Drugs       Date:  1982-10       Impact factor: 9.546

Review 10.  Muscle damage and endurance events.

Authors:  R B Armstrong
Journal:  Sports Med       Date:  1986 Sep-Oct       Impact factor: 11.136
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