Literature DB >> 7360002

Inhibition of EMT6 tumor growth by interference with polyamine biosynthesis; effects of alpha-difluoromethylornithine, an irreversible inhibitor of ornithine decarboxylase.

N J Prakash, P J Schechter, P S Mamont, J Grove, J Koch-Weser, A Sjoerdsma.   

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Year:  1980        PMID： 7360002     DOI： 10.1016/0024-3205(80)90292-1

Source DB:  PubMed          Journal:  Life Sci        ISSN： 0024-3205            Impact factor:   5.037


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  22 in total

1.  Phase I trial and pharmacokinetic study of intravenous and oral alpha-difluoromethylornithine.

Authors:  C A Griffin; M Slavik; S C Chien; J Hermann; G Thompson; O Blanc; G D Luk; S B Baylin; M D Abeloff
Journal:  Invest New Drugs       Date:  1987       Impact factor: 3.850

2.  Transfer of intestine-derived diamines into tumour cells during treatment of Ehrlich-ascites--carcinoma-bearing mice with polyamine anti-metabolites.

Authors:  A Kallio; P Nikula; J Jänne
Journal:  Biochem J       Date:  1984-03-01       Impact factor: 3.857

Review 3.  Cancer pharmacoprevention: Targeting polyamine metabolism to manage risk factors for colon cancer.

Authors:  Eugene W Gerner; Elizabeth Bruckheimer; Alfred Cohen
Journal:  J Biol Chem       Date:  2018-10-24       Impact factor: 5.157

4.  The additive effect of alpha-difluoromethylornithine (DFMO) and radiation therapy on a rat glioma model.

Authors:  T Tsukahara; M Tamura; H Yamazaki; H Kurihara; S Matsuzaki
Journal:  J Cancer Res Clin Oncol       Date:  1992       Impact factor: 4.553

5.  alpha-Difluoromethylornithine, an irreversible inhibitor of ornithine decarboxylase, inhibits tumor promoter-induced polyamine accumulation and carcinogenesis in mouse skin.

Authors:  C E Weeks; A L Herrmann; F R Nelson; T J Slaga
Journal:  Proc Natl Acad Sci U S A       Date:  1982-10       Impact factor: 11.205

6.  Failure of treatment with alpha-difluoromethylornithine against secondary multilocular echinococcosis in mice.

Authors:  S Miyaji; K Katakura; S Matsufuji; Y Murakami; S Hayashi; Y Oku; M Okamoto; M Kamiya
Journal:  Parasitol Res       Date:  1993       Impact factor: 2.289

7.  Role of diamine oxidase during the treatment of tumour-bearing mice with combinations of polyamine anti-metabolites.

Authors:  A Kallio; J Jänne
Journal:  Biochem J       Date:  1983-06-15       Impact factor: 3.857

8.  Polyamine biosynthesis is required for the maintenance of peripheral blood cell elements in the rat.

Authors:  G D Luk; S J Sharkis; M D Abeloff; P P McCann; A Sjoerdsma; S B Baylin
Journal:  Proc Natl Acad Sci U S A       Date:  1983-08       Impact factor: 11.205

9.  Role of polyamines in the growth of hormone-responsive experimental breast cancer in vivo.

Authors:  A Manni; B Badger; G Luk; C Wright; R Caplan; H Rockette; M Bartholomew; S R Ahmed
Journal:  Breast Cancer Res Treat       Date:  1988-07       Impact factor: 4.872

10.  Indirect evidence for a strict negative control of S-adenosyl-L-methionine decarboxylase by spermidine in rat hepatoma cells.

Authors:  P S Mamont; A M Joder-Ohlenbusch; M Nussli; J Grove
Journal:  Biochem J       Date:  1981-05-15       Impact factor: 3.857
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