| Literature DB >> 7350525 |
Abstract
A tRNATrp was purified from rabbit reticulocytes which suppresses the UGA termination codon of beta-haemoglobin mRNA. Evidence is presented that the beta-haemoglobin readthrough protein is found in reticulocyte translations and intact cells. Some natural readthrough proteins perform essential functions; they are synthesised through suppression of UGA or UAG but not UAA termination codons.Entities:
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Year: 1980 PMID: 7350525 DOI: 10.1038/283041a0
Source DB: PubMed Journal: Nature ISSN: 0028-0836 Impact factor: 49.962