Literature DB >> 7347562

Effects of vancomycin on renal function in rats.

G R Aronoff, R S Sloan, C B Dinwiddie, M D Glant, N S Fineberg, F C Luft.   

Abstract

To assess the effects of vancomycin on the kidney, we gave rats doses of 10, 50, 100, 200, and 400 mg/kg per day. Creatinine clearance and urine protein excretion did not differ significantly from the control values. Urine osmolality was unchanged. Mild histological changes occurred in rats given the highest dose. We conclude that although histopathological changes occurred at high doses, vancomycin does not alter renal function in rats.

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Year:  1981        PMID： 7347562      PMCID： PMC181415          DOI： 10.1128/AAC.19.2.306

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  7 in total

1.  Vancomycin therapy of staphylococcal infections.

Authors:  W M KIRBY
Journal:  Antibiot Chemother       Date:  1963

2.  Toxicologic studies on vancomycin and polyethylene glycol 200.

Authors:  C C LEE; R C ANDERSON
Journal:  Toxicol Appl Pharmacol       Date:  1962-03       Impact factor: 4.219

3.  Vancomycin.

Authors:  J E Geraci
Journal:  Mayo Clin Proc       Date:  1977-10       Impact factor: 7.616

4.  A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding.

Authors:  M M Bradford
Journal:  Anal Biochem       Date:  1976-05-07       Impact factor: 3.365

Review 5.  Antibiotics and the kidney.

Authors:  P Kovnat; E Labovitz; S P Levison
Journal:  Med Clin North Am       Date:  1973-07       Impact factor: 5.456

6.  Guidelines for drug therapy in renal failure.

Authors:  W M Bennett; I Singer; T Golper; P Feig; C J Coggins
Journal:  Ann Intern Med       Date:  1977-06       Impact factor: 25.391

Review 7.  Vancomycin revisited.

Authors:  F V Cook; W E Farrar
Journal:  Ann Intern Med       Date:  1978-06       Impact factor: 25.391
  7 in total
  15 in total

1.  Evaluation of Vancomycin Exposures Associated with Elevations in Novel Urinary Biomarkers of Acute Kidney Injury in Vancomycin-Treated Rats.

Authors:  Nathaniel J Rhodes; Walter C Prozialeck; Thomas P Lodise; Natarajan Venkatesan; J Nicholas O'Donnell; Gwendolyn Pais; Cameron Cluff; Peter C Lamar; Michael N Neely; Anil Gulati; Marc H Scheetz
Journal:  Antimicrob Agents Chemother       Date:  2016-09-23       Impact factor: 5.191

2.  Intrarenal distribution of vancomycin in endotoxemic rats.

Authors:  M Ngeleka; P Auclair; D Tardif; D Beauchamp; M G Bergeron
Journal:  Antimicrob Agents Chemother       Date:  1989-09       Impact factor: 5.191

3.  Cathodic Electrical Stimulation Combined With Vancomycin Enhances Treatment of Methicillin-resistant Staphylococcus aureus Implant-associated Infections.

Authors:  Scott Nodzo; Menachem Tobias; Lisa Hansen; Nicole R Luke-Marshall; Ross Cole; Linda Wild; Anthony A Campagnari; Mark T Ehrensberger
Journal:  Clin Orthop Relat Res       Date:  2015-09       Impact factor: 4.176

Review 4.  Vancomycin and the Risk of AKI: A Systematic Review and Meta-Analysis.

Authors:  Abhisekh Sinha Ray; Ammar Haikal; Kassem A Hammoud; Alan S L Yu
Journal:  Clin J Am Soc Nephrol       Date:  2016-11-28       Impact factor: 8.237

Review 5.  Vancomycin ototoxicity and nephrotoxicity. A review.

Authors:  G R Bailie; D Neal
Journal:  Med Toxicol Adverse Drug Exp       Date:  1988 Sep-Oct

Review 6.  Pharmacokinetic optimisation of vancomycin therapy.

Authors:  W G Leader; M H Chandler; M Castiglia
Journal:  Clin Pharmacokinet       Date:  1995-04       Impact factor: 6.447

Review 7.  Clinical pharmacokinetics of vancomycin.

Authors:  G R Matzke; G G Zhanel; D R Guay
Journal:  Clin Pharmacokinet       Date:  1986 Jul-Aug       Impact factor: 6.447

8.  Cathodic Voltage-controlled Electrical Stimulation Plus Prolonged Vancomycin Reduce Bacterial Burden of a Titanium Implant-associated Infection in a Rodent Model.

Authors:  Scott R Nodzo; Menachem Tobias; Richard Ahn; Lisa Hansen; Nicole R Luke-Marshall; Craig Howard; Linda Wild; Anthony A Campagnari; Mark T Ehrensberger
Journal:  Clin Orthop Relat Res       Date:  2016-07       Impact factor: 4.176

9.  Alanine aminopeptidase and beta 2-microglobulin excretion in patients receiving vancomycin and gentamicin.

Authors:  M J Rybak; J J Frankowski; D J Edwards; L M Albrecht
Journal:  Antimicrob Agents Chemother       Date:  1987-10       Impact factor: 5.191

10.  Vancomycin enhancement of experimental tobramycin nephrotoxicity.

Authors:  C A Wood; S J Kohlhepp; P W Kohnen; D C Houghton; D N Gilbert
Journal:  Antimicrob Agents Chemother       Date:  1986-07       Impact factor: 5.191
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