Literature DB >> 7342978

Tricarboxylic acid cycle flux and enzyme activities in the isolated working rat heart.

G J Cooney, H Taegtmeyer, E A Newsholme.   

Abstract

Flux through the tricarboxylic acid cycle was calculated from oxygen consumption in hearts perfused near the physiological work load. Activities of citrate synthase, 2-oxoglutarate dehydrogenase and succinate dehydrogenase were measured in the same hearts. Only the activities of 2-oxoglutarate dehydrogenase correlated with calculated fluxes through the cycle.

Entities:  

Mesh：

Substances：

Year:  1981        PMID： 7342978      PMCID： PMC1163594          DOI： 10.1042/bj2000701

Source DB:  PubMed          Journal:  Biochem J        ISSN： 0264-6021            Impact factor:   3.857


  8 in total

1.  Effects of indomethacin on respiration and the alpha-glycerolphosphate shuttle in rat kidney mitochondria.

Authors:  G J Cooney; A G Dawson
Journal:  Biochem Pharmacol       Date:  1979-04-01       Impact factor: 5.858

2.  The activities of 2-oxoglutarate dehydrogenase and pyruvate dehydrogenase in hearts and mammary glands from ruminants and non-ruminants.

Authors:  G Read; B Crabtree; G H Smith
Journal:  Biochem J       Date:  1977-05-15       Impact factor: 3.857

3.  Activities of citrate synthase and NAD+-linked and NADP+-linked isocitrate dehydrogenase in muscle from vertebrates and invertebrates.

Authors:  P R Alp; E A Newsholme; V A Zammit
Journal:  Biochem J       Date:  1976-03-15       Impact factor: 3.857

4.  Use of enzyme activities as indices of maximum rates of fuel utilization.

Authors:  E A Newsholme; B Crabtree; V A Zammit
Journal:  Ciba Found Symp       Date:  1979

5.  Mitochondrial-cytosolic interactions in perfused rat heart. Role of coupled transamination in repletion of citric acid cycle intermediates.

Authors:  B Safer; J R Williamson
Journal:  J Biol Chem       Date:  1973-04-10       Impact factor: 5.157

6.  Localization of the glycerol-phosphate dehydrogenase in the outer phase of the mitochondrial inner membrane.

Authors:  M Klingenberg
Journal:  Eur J Biochem       Date:  1970-04

Review 7.  Succinic thiokinase and metabolic control.

Authors:  J H Ottaway; J A McClellan; C L Saunderson
Journal:  Int J Biochem       Date:  1981

8.  Utilization of energy-providing substrates in the isolated working rat heart.

Authors:  H Taegtmeyer; R Hems; H A Krebs
Journal:  Biochem J       Date:  1980-03-15       Impact factor: 3.857
  8 in total
  37 in total

Review 1.  Alpha-ketoglutarate dehydrogenase: a target and generator of oxidative stress.

Authors:  Laszlo Tretter; Vera Adam-Vizi
Journal:  Philos Trans R Soc Lond B Biol Sci       Date:  2005-12-29       Impact factor: 6.237

2.  Energy metabolism, enzymatic flux capacities, and metabolic flux rates in flying honeybees.

Authors:  R K Suarez; J R Lighton; B Joos; S P Roberts; J F Harrison
Journal:  Proc Natl Acad Sci U S A       Date:  1996-10-29       Impact factor: 11.205

3.  Exercise training induces similar elevations in the activity of oxoglutarate dehydrogenase and peak oxygen uptake in the human quadriceps muscle.

Authors:  Eva Blomstrand; Peter Krustrup; Hans Søndergaard; Göran Rådegran; José A L Calbet; Bengt Saltin
Journal:  Pflugers Arch       Date:  2011-05-25       Impact factor: 3.657

4.  Maximum rate of oxygen uptake by human skeletal muscle in relation to maximal activities of enzymes in the Krebs cycle.

Authors:  E Blomstrand; G Rådegran; B Saltin
Journal:  J Physiol       Date:  1997-06-01       Impact factor: 5.182

5.  Obesogenic high fat western diet induces oxidative stress and apoptosis in rat heart.

Authors:  Kalpana Ballal; Christopher R Wilson; Romain Harmancey; Heinrich Taegtmeyer
Journal:  Mol Cell Biochem       Date:  2010-07-31       Impact factor: 3.396

6.  Enzymic and metabolic adaptations in the gastrocnemius, plantaris and soleus muscles of hypocaloric rats.

Authors:  M S Ardawi; M F Majzoub; I M Masoud; E A Newsholme
Journal:  Biochem J       Date:  1989-07-01       Impact factor: 3.857

Review 7.  Matrix revisited: mechanisms linking energy substrate metabolism to the function of the heart.

Authors:  Andrew N Carley; Heinrich Taegtmeyer; E Douglas Lewandowski
Journal:  Circ Res       Date:  2014-02-14       Impact factor: 17.367

8.  Qualitative modification of muscle metabolic organization with thermal acclimation of rainbow trout, Oncorhynchus mykiss.

Authors:  H Guderley; A Gawlicka
Journal:  Fish Physiol Biochem       Date:  1992-08       Impact factor: 2.794

9.  Metabolic effects of feeding a high protein/low carbohydrate diet as compared to a low protein/high carbohydrate diet to rainbow troutSalmo gairdneri.

Authors:  M J Walton
Journal:  Fish Physiol Biochem       Date:  1986-01       Impact factor: 2.794

10.  Biochemical adaptation in the skeletal muscle of rats depleted of creatine with the substrate analogue beta-guanidinopropionic acid.

Authors:  E A Shoubridge; R A Challiss; D J Hayes; G K Radda
Journal:  Biochem J       Date:  1985-11-15       Impact factor: 3.857
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.