Literature DB >> 7338208

A computer program for estimating LD50 and its confidence limits using modified Behrens-Reed-Muench cumulant method.

A K Thakur, W L Fezio.   

Abstract

A FORTRAN IV program is developed for simple and quick estimation of LD50 and its confidence intervals from quantal dose-response data. The algorithm is based on a modification of the Behrens-Reed-Muench cumulant method. Under ideal experimental design, the method produces results comparable to the ones by statistically more accurate maximum likelihood method using the Logit or the Probit transformation. The procedure, as implemented, can also be easily performed on a small hand-held calculator.

Mesh：

Year:  1981        PMID： 7338208     DOI： 10.3109/01480548109018136

Source DB:  PubMed          Journal:  Drug Chem Toxicol        ISSN： 0148-0545            Impact factor:   3.356


  21 in total

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5.  ICAM-5 modulates cytokine/chemokine production in the CNS during the course of herpes simplex virus type 1 infection.

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Authors:  Rong Hai; Mirco Schmolke; Victor H Leyva-Grado; Rajagowthamee R Thangavel; Irina Margine; Eric L Jaffe; Florian Krammer; Alicia Solórzano; Adolfo García-Sastre; Peter Palese; Nicole M Bouvier
Journal:  Nat Commun       Date:  2013       Impact factor: 14.919

10.  Pulmonary immune responses to 2009 pandemic influenza A (H1N1) virus in mice.

Authors:  Jin Lv; Dan Wang; Yan-Hong Hua; Shi-Jia Pei; Jin Wang; Wen-Wei Hu; Xi-Liang Wang; Na Jia; Qi-Sheng Jiang
Journal:  BMC Infect Dis       Date:  2014-04-12       Impact factor: 3.090
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