Literature DB >> 7333321

A comparison between terminally radioiodinated hexadecenoic acid (125I-HA) and heptadecanoic acid (131I-H0A) in the dog heart.

E E van der Wall, G Westera, G A Heidendal, W den Hollander.   

Abstract

The regional myocardial distribution of 125I-16-iodo-9-hexadecenoic acid (125I-HA) and 131I-17-iodo-heptadecanoic acid (131I-H0A) was determined in one normal dog and in five dogs within 5 min after coronary artery occlusion. The total myocardial uptake of 125I-H A was about 40% lower than that of 131I-H0A. The ratio 125I:131I in the normally perfused parts of the myocardium was 0.38-0.81, but the ischemic tissue showed a higher 125I:131I ratio (0.87-1.03), due to lower accumulation of 131I-H0A in ischemic myocardium. We conclude that both radioiodinated fatty acids are reliable indicators of myocardial perfusion and that iodo-heptadecanoic acid, when labeled with 123I, may be preferred to iodo-hexadecenoic acid as the labeled fatty acid for cardiac imaging agent in clinical practice.

Entities:  

Mesh：

Substances：

Year:  1981        PMID： 7333321     DOI： 10.1007/bf00252673

Source DB:  PubMed          Journal:  Eur J Nucl Med        ISSN： 0340-6997


  16 in total

1.  USE OF RADIOIODINATED FATTY ACID FOR PHOTOSCANS OF THE HEART.

Authors:  J R EVANS; R W GUNTON; R G BAKER; D S BEANLANDS; J C SPEARS
Journal:  Circ Res       Date:  1965-01       Impact factor: 17.367

2.  Uptake and metabolism of fatty acids and analogues by cultured cardiac cells from chick embryo.

Authors:  D Samuel; S Paris; G Ailhaud
Journal:  Eur J Biochem       Date:  1976-05-01

Review 3.  Myocardial utilization of carbohydrate and lipids.

Authors:  J R Neely; M J Rovetto; J F Oram
Journal:  Prog Cardiovasc Dis       Date:  1972 Nov-Dec       Impact factor: 8.194

4.  Comparison of regional myocardial perfusion determined by ionic potassium-43 to that determinated by microspheres.

Authors:  E K Prokop; H W Strauss; J Shaw; B Pitt; H N Wagner
Journal:  Circulation       Date:  1974-11       Impact factor: 29.690

5.  Mapping of left ventricular blood flow with radioactive microspheres in experimental coronary artery occlusion.

Authors:  L C Becker; R Ferreira; M Thomas
Journal:  Cardiovasc Res       Date:  1973-05       Impact factor: 10.787

6.  Experimental myocardial imaging with 131 I-labeled oleic acid.

Authors:  F J Bonte; K D Graham; J G Moore
Journal:  Radiology       Date:  1973-07       Impact factor: 11.105

7.  Myocardial extraction of labeled long-chain fatty acid analogs (38509).

Authors:  N D Poe; G D Rovinson; N S MacDonald
Journal:  Proc Soc Exp Biol Med       Date:  1975-01

8.  Experimental basis of myocardial imaging with 123I-labeled hexadecenoic acid.

Authors:  N D Poe; G D Robinson; L S Graham; N S MacDonald
Journal:  J Nucl Med       Date:  1976-12       Impact factor: 10.057

9.  Myocardial imaging with 123I-hexadecenoic acid.

Authors:  N D Poe; G D Robinson; F W Zielinski; W R Cabeen; J W Smith; A S Gomes
Journal:  Radiology       Date:  1977-08       Impact factor: 11.105

10.  A comparison between terminally radioiodinated hexadecenoic acid (I-HA) and 201Tl-thallium chloride in the dog heart. Implications for the use of I-HA for myocardial imaging.

Authors:  G Westera; E E van der Wall; G A Heidendal; G C van den Bos
Journal:  Eur J Nucl Med       Date:  1980-08
View more
  2 in total

Review 1.  Cardiac metabolism: a technical spectrum of modalities including positron emission tomography, single-photon emission computed tomography, and magnetic resonance spectroscopy.

Authors:  R Valkema; B L van Eck-Smit; E E van der Wall
Journal:  J Nucl Cardiol       Date:  1994 Nov-Dec       Impact factor: 5.952

2.  Influence of propranolol on uptake of radioiodinated heptadecanoic acid and thallium-201 in the dog heart.

Authors:  E E van der Wall; G Westera; M J van Eenige; S Scholtalbers; F C Visser; W den Hollander; J P Roos
Journal:  Eur J Nucl Med       Date:  1983
  2 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.