Literature DB >> 7325971

Identification and characterization of a phospholipase C activity in resident mouse peritoneal macrophages. Inhibition of the enzyme by phenothiazines.

P D Wightman, M E Dahlgren, J C Hall, P Davies, R J Bonney.   

Abstract

Resident mouse peritoneal macrophages contain a phospholipase C of high activity that is specific for phosphatidylinositol. The activity has a neutral pH optimum, is Ca(2+)-dependent and has a maximum reaction velocity of 525nmol/h per mg of protein. Certain phenothiazines are potent inhibitors of this activity.

Entities:  

Mesh：

Substances：

Year:  1981        PMID： 7325971      PMCID： PMC1163156          DOI： 10.1042/bj1970523

Source DB:  PubMed          Journal:  Biochem J        ISSN： 0264-6021            Impact factor:   3.857


  26 in total

1.  A rapid method of total lipid extraction and purification.

Authors:  E G BLIGH; W J DYER
Journal:  Can J Biochem Physiol       Date:  1959-08

2.  Stimulation of phosphatidylinositol turnover in the macrophage plasma membrane: a possible mechanism for signal transmission.

Authors:  H M Ogmundsdóttir; D M Weir
Journal:  Immunology       Date:  1979-07       Impact factor: 7.397

3.  Membrane function and metabolism in phagocytic cells.

Authors:  M L Karnovsky; A W Shafer; R H Cagan; R C Graham; M J Karnovsky; E A Glass; K Saito
Journal:  Trans N Y Acad Sci       Date:  1966-04

4.  Ca replacement by cationic amphiphilic drugs from lipid monolayers.

Authors:  H Lüllmann; H Plösch; A Ziegler
Journal:  Biochem Pharmacol       Date:  1980-11-01       Impact factor: 5.858

5.  Selective inhibitors of lecithin biosynthesis in mouse peritoneal macrophages.

Authors:  R J Bonney; P D Wightman; P Davies
Journal:  Biochem Pharmacol       Date:  1979-08-15       Impact factor: 5.858

6.  Relationship of prostaglandin secretion by rabbit alveolar macrophages to phagocytosis and lysosomal enzyme release.

Authors:  W Hsueh; C Kuhn; P Needleman
Journal:  Biochem J       Date:  1979-11-15       Impact factor: 3.857

7.  Antigen-antibody complexes stimulate the synthesis and release of prostaglandins by mouse peritoneal macrophages.

Authors:  R J Bonney; P Naruns; P Davies; J L Humes
Journal:  Prostaglandins       Date:  1979-10

8.  [Identification and characterization of two phospholipase A2 activities in resident mouse peritoneal macrophages].

Authors:  P D Wightman; J L Humes; P Davies; R J Bonney
Journal:  Biochem J       Date:  1981-05-01       Impact factor: 3.857

9.  Effect of RNA and protein synthesis inhibitors on the release of inflammatory mediators by macrophages responding to phorbol myristate acetate.

Authors:  R J Bonney; P D Wightman; M E Dahlgren; P Davies; F A Kuehl; J L Humes
Journal:  Biochim Biophys Acta       Date:  1980-12-15

10.  Regulation of arachidonic acid metabolites in macrophages.

Authors:  W A Scott; J M Zrike; A L Hamill; J Kempe; Z A Cohn
Journal:  J Exp Med       Date:  1980-08-01       Impact factor: 14.307
View more
  11 in total

Review 1.  Group XV phospholipase A₂, a lysosomal phospholipase A₂.

Authors:  James A Shayman; Robert Kelly; Jessica Kollmeyer; Yongqun He; Akira Abe
Journal:  Prog Lipid Res       Date:  2010-11-11       Impact factor: 16.195

2.  Ionophore A23187 induces a refractory state in thrombin-activated release of inositol phosphates.

Authors:  G Moscat; F Moreno; S Iglesias; P Garcia-Barreno; A M Municio
Journal:  Biochem J       Date:  1986-09-15       Impact factor: 3.857

Review 3.  Mononuclear phagocytes and eicosanoids: aspects of their synthesis and biological activities.

Authors:  U F Schade; I Burmeister; E Elekes; R Engel; D T Wolter
Journal:  Blut       Date:  1989-12

4.  Lipopolysaccharide priming of human neutrophils for an enhanced respiratory burst. Role of intracellular free calcium.

Authors:  J R Forehand; M J Pabst; W A Phillips; R B Johnston
Journal:  J Clin Invest       Date:  1989-01       Impact factor: 14.808

5.  Biosynthesis of paf-acether. Paf-acether but not leukotriene C4 production is impaired in cultured macrophages.

Authors:  A Dulioust; E Vivier; N Meslier; R Roubin; I Haye-Legrand; J Benveniste
Journal:  Biochem J       Date:  1989-10-01       Impact factor: 3.857

6.  Phosphatidylinositol hydrolysis in isolated guinea-pig islets of Langerhans.

Authors:  M P Schrey; W Montague
Journal:  Biochem J       Date:  1983-11-15       Impact factor: 3.857

7.  Leishmania and Trypanosoma surface glycoproteins have a common glycophospholipid membrane anchor.

Authors:  C Bordier; R J Etges; J Ward; M J Turner; M L Cardoso de Almeida
Journal:  Proc Natl Acad Sci U S A       Date:  1986-08       Impact factor: 11.205

8.  The effect of sn-2 fatty acid substitution on phospholipase C enzyme activities.

Authors:  J S Bomalaski; M A Clark
Journal:  Biochem J       Date:  1987-06-15       Impact factor: 3.857

9.  Inhibition of concanavalin A-induced phosphatidylinositol turnover and lysosomal enzyme release by cyclic AMP-elevating agents in rat peritoneal macrophages.

Authors:  T Matsubara; M Fujii; H Ishikawa; K Hirohata
Journal:  Rheumatol Int       Date:  1983       Impact factor: 2.631

10.  Evidence for sequential signals in the induction of the arachidonic acid cascade in macrophages.

Authors:  A A Aderem; W A Scott; Z A Cohn
Journal:  J Exp Med       Date:  1986-01-01       Impact factor: 14.307
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.