Literature DB >> 7317004

Dansyl (5-dimethylaminonaphthalene-1-sulphonyl)-heparin binds antithrombin III and platelet factor 4 at separate sites.

M W Piepkorn.   

Abstract

Antithrombin III binds to, and thereby augments the fluorescence of, dansyl-(5-dimethylaminonaphthalene-1-sulphonyl)-heparin; platelet factor 4 binding to the fluorescent heparin has little of this effect. Competition studies in which antithrombin III competes with platelet factor 4 for heparin binding demonstrate that heparin can simultaneously bind both proteins.

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Year:  1981        PMID： 7317004      PMCID： PMC1163043          DOI： 10.1042/bj1960649

Source DB:  PubMed          Journal:  Biochem J        ISSN： 0264-6021            Impact factor:   3.857


  9 in total

1.  A modified uronic acid carbazole reaction.

Authors:  T BITTER; H M MUIR
Journal:  Anal Biochem       Date:  1962-10       Impact factor: 3.365

Review 2.  Biologic actions of heparin.

Authors:  R D Rosenberg
Journal:  Semin Hematol       Date:  1977-10       Impact factor: 3.851

3.  Isolation, crystallization, and primary amino acid sequence of human platelet factor 4.

Authors:  M Hermodson; G Schmer; K Kurachi
Journal:  J Biol Chem       Date:  1977-09-25       Impact factor: 5.157

4.  Platelet antiheparin proteins and antithrombin III interact with different binding sites on heparin molecule.

Authors:  S Niewiarowski; B Rucinski; P James; U Lindahl
Journal:  FEBS Lett       Date:  1979-06-01       Impact factor: 4.124

5.  The molecular-weight-dependence of the anti-coagulant activity of heparin.

Authors:  T C Laurent; A Tengblad; L Thunberg; M Höök; U Lindahl
Journal:  Biochem J       Date:  1978-11-01       Impact factor: 3.857

6.  Neutralization of antithrombin VI (fibrinogen breakdown products) with platelet antiheparin factor (platelet factor 4).

Authors:  S Niewiarowski; R Farbiszewski; A Poplawski
Journal:  Thromb Diath Haemorrh       Date:  1965-11-15

7.  Characterization of human, bovine, and horse antithrombin III.

Authors:  K Kurachi; G Schmer; M A Hermodson; D C Teller; E W Davie
Journal:  Biochemistry       Date:  1976-01-27       Impact factor: 3.162

8.  Purification and binding properties of human platelet factor four.

Authors:  R I Handin; H J Cohen
Journal:  J Biol Chem       Date:  1976-07-25       Impact factor: 5.157

9.  A simple two-step isolation procedure for human and bovine antithrombin II/III (heparin cofactor): a comparison of two methods.

Authors:  E Thaler; G Schmer
Journal:  Br J Haematol       Date:  1975-10       Impact factor: 6.998
  9 in total
  4 in total

1.  Binding of heparin to human platelet factor 4.

Authors:  S W Cowan; E N Bakshi; K J Machin; N W Isaacs
Journal:  Biochem J       Date:  1986-03-01       Impact factor: 3.857

2.  Thermodynamic Affinity and Nature of Forces Defining Glycosaminoglycan-Protein Systems Using Fluorescence Spectroscopy.

Authors:  Rio S Boothello; Umesh Desai
Journal:  Methods Mol Biol       Date:  2022

3.  Binding of platelet factor 4 to heparin oligosaccharides.

Authors:  J Denton; D A Lane; L Thunberg; A M Slater; U Lindahl
Journal:  Biochem J       Date:  1983-02-01       Impact factor: 3.857

Review 4.  Role of platelet chemokines, PF-4 and CTAP-III, in cancer biology.

Authors:  Katerina Pilatova; Kristina Greplova; Regina Demlova; Beatrix Bencsikova; Giannoula Lakka Klement; Lenka Zdrazilova-Dubska
Journal:  J Hematol Oncol       Date:  2013-06-24       Impact factor: 17.388
  4 in total

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