Literature DB >> 7316984

Inhibition of dihydropteridine reductase by dopamine.

S E Purdy, J A Blair, P A Barford.   

Abstract

Dihydropteridine reductase has been purified 900-fold from rat liver. Dopamine inhibited the enzyme up to 50% at a concentration of 0.11mm. In the presence of dopamine the enzyme gave non-hyperbolic v-against-[S] plots. This enzyme may have a role in control of dopamine biosynthesis.

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Year:  1981        PMID： 7316984      PMCID： PMC1162951          DOI： 10.1042/bj1950769

Source DB:  PubMed          Journal:  Biochem J        ISSN： 0264-6021            Impact factor:   3.857


  8 in total

1.  Phenylketonuria due to a deficiency of dihydropteridine reductase.

Authors:  S Kaufman; N A Holtzman; S Milstien; L J Butler; A Krumholz
Journal:  N Engl J Med       Date:  1975-10-16       Impact factor: 91.245

2.  STUDIES ON THE STRUCTURE OF THE PRIMARY OXIDATION PRODUCT FORMED FROM TETRAHYDROPTERIDINES DURING PHENYLALAMINE HYDROXYLATION.

Authors:  S KAUFMAN
Journal:  J Biol Chem       Date:  1964-01       Impact factor: 5.157

3.  The isolation and characterization of dihydropteridine reductase from sheep liver.

Authors:  J E Craine; E S Hall; S Kaufman
Journal:  J Biol Chem       Date:  1972-10-10       Impact factor: 5.157

4.  A naphthoquinone adsorbent for affinity chromatography of human dihydropteridine reductase.

Authors:  R G Cotton; I Jennings
Journal:  Eur J Biochem       Date:  1978-02-01

5.  In vivo enhancement of tyrosine hydroxylation in rat striatum by tetrahydrobiopterin.

Authors:  R Kettler; G Bartholini; A Pletscher
Journal:  Nature       Date:  1974-05-31       Impact factor: 49.962

6.  Presynaptic regulation of tyrosine hydroxylase activity in rat striatal synaptosomes by dopamine analogs.

Authors:  W G Waggoner; J McDermed; H J Leighton
Journal:  Mol Pharmacol       Date:  1980-07       Impact factor: 4.436

7.  The purification of rat and sheep liver dihydropteridine reductases by affinity chromatography on methotrexate-sepharose.

Authors:  S Webber; T L Deits; W R Snyder; J M Whiteley
Journal:  Anal Biochem       Date:  1978-02       Impact factor: 3.365

8.  Properties of purifed quinonoid dihydropterin reductase.

Authors:  S Cheema; S J Soldin; A Knapp; K T Hofmann; K G Scrimgeour
Journal:  Can J Biochem       Date:  1973-09
  8 in total
  1 in total

1.  Km and kcat. values for [6,6,7,7-2H]7,8(6H)-dihydropterin and 2,6-diamino-5-iminopyrimidin-4-one with dihydropteridine reductase.

Authors:  W L Armarego; D Randles; H Taguchi
Journal:  Biochem J       Date:  1983-05-01       Impact factor: 3.857
  1 in total

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