| Literature DB >> 731415 |
I C Caldwell, S Mahmood, M Weatherall.
Abstract
A pharmacokinetic model incorporating 14 compartments and 29 transfer coefficients has been developed from experimental data obtained after intravenous administration of a single dose to describe the distribution of doxantrazole in the rate. The distribution calculated from the model agreed closely with that determined experimentally. In addition, the model was able to predict with considerable accuracy the distribution of doxantrazole after repeated dosing.Entities:
Mesh：
Substances：
Year: 1978 PMID： 731415 DOI： 10.1007/bf01062107
Source DB: PubMed Journal: J Pharmacokinet Biopharm ISSN： 0090-466X