Literature DB >> 7312952

Photorepair of pyrimidine dimers in human skin in vivo.

S M D'Ambrosio, J W Whetstone, L Slazinski, E Lowney.   

Abstract

The exposure of human skin in vivo to UV radiation emitted from a sunlamp induces the formation of pyrimidine dimers. The number of dimers, as detected by UV-endonuclease, decreases following exposure of the UV-irradiated skin to visible wavelengths of light. These results suggest that humans possess a mechanism by which pyrimidine dimers are photorepaired upon illumination of human skin in vivo with visible light.

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Year:  1981        PMID： 7312952

Source DB:  PubMed          Journal:  Photochem Photobiol        ISSN： 0031-8655            Impact factor:   3.421


  8 in total

1.  Photoreactivation rescue and hypermutability of ultraviolet-irradiated excisionless Drosophila melanogaster larvae.

Authors:  H Ryo; S Kondo
Journal:  Proc Natl Acad Sci U S A       Date:  1986-05       Impact factor: 11.205

2.  Side effects in excimer corneal surgery. DNA damage as a result of 193 nm excimer laser radiation.

Authors:  T Seiler; T Bende; K Winckler; J Wollensak
Journal:  Graefes Arch Clin Exp Ophthalmol       Date:  1988       Impact factor: 3.117

3.  Photoreactivation of UV-induced pyrimidine dimers and erythema in the marsupial Monodelphis domestica.

Authors:  R D Ley
Journal:  Proc Natl Acad Sci U S A       Date:  1985-04       Impact factor: 11.205

4.  Wavelength dependence of pyrimidine dimer formation in DNA of human skin irradiated in situ with ultraviolet light.

Authors:  S E Freeman; H Hacham; R W Gange; D J Maytum; J C Sutherland; B M Sutherland
Journal:  Proc Natl Acad Sci U S A       Date:  1989-07       Impact factor: 11.205

5.  Human white blood cells contain cyclobutyl pyrimidine dimer photolyase.

Authors:  B M Sutherland; P V Bennett
Journal:  Proc Natl Acad Sci U S A       Date:  1995-10-10       Impact factor: 11.205

6.  Evidence for lack of DNA photoreactivating enzyme in humans.

Authors:  Y F Li; S T Kim; A Sancar
Journal:  Proc Natl Acad Sci U S A       Date:  1993-05-15       Impact factor: 11.205

Review 7.  Chemical carcinogens: a review of the science and its associated principles. U.S. Interagency Staff Group on Carcinogens.

Authors: 
Journal:  Environ Health Perspect       Date:  1986-08       Impact factor: 9.031

8.  Identification of the molecular target for the suppression of contact hypersensitivity by ultraviolet radiation.

Authors:  L A Applegate; R D Ley; J Alcalay; M L Kripke
Journal:  J Exp Med       Date:  1989-10-01       Impact factor: 14.307
  8 in total

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