Literature DB >> 7309726

26-Hydroxycholesterol. Identification and quantitation in human serum.

N B Javitt, E Kok, S Burstein, B Cohen, J Kutscher.   

Abstract

Using isotope dilution mass spectrometry, 26-hydroxycholesterol was identified in the serum of normal adults. Total values ranged from 9.2 to 25.6 micrograms/100 ml of which 31-35% was free sterol. Density gradient ultracentrifugation indicates that the steroid is distributed among the low and high density lipoproteins.

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Year:  1981        PMID： 7309726

Source DB:  PubMed          Journal:  J Biol Chem        ISSN： 0021-9258            Impact factor:   5.157


  10 in total

1.  Plasmid lipid and lipoprotein pattern in the Inuit of the Keewatin district of the Northwest territories.

Authors:  Michael J B Kutryk; Bram Ramjiawan
Journal:  Mol Cell Biochem       Date:  2003-04       Impact factor: 3.396

2.  Effects of cholesterol and 25-hydroxycholesterol on smooth muscle cell and endothelial cell growth.

Authors:  D C Cox; K Comai; A L Goldstein
Journal:  Lipids       Date:  1988-02       Impact factor: 1.880

3.  Activation of the orphan nuclear receptor steroidogenic factor 1 by oxysterols.

Authors:  D S Lala; P M Syka; S B Lazarchik; D J Mangelsdorf; K L Parker; R A Heyman
Journal:  Proc Natl Acad Sci U S A       Date:  1997-05-13       Impact factor: 11.205

4.  Metabolism of 3 beta-hydroxycholest-5-en-26-oic acid in hamsters.

Authors:  Y Ayaki; E Kok; N B Javitt
Journal:  Experientia       Date:  1990-03-15

5.  Cholesterol and bile acid synthesis in Hep G2 cells. Metabolic effects of 26- and 7 alpha-hydroxycholesterol.

Authors:  N B Javitt; K Budai
Journal:  Biochem J       Date:  1989-09-15       Impact factor: 3.857

6.  Production of oxidized lipids during modification of low-density lipoprotein by macrophages or copper.

Authors:  K L Carpenter; G M Wilkins; B Fussell; J A Ballantine; S E Taylor; M J Mitchinson; D S Leake
Journal:  Biochem J       Date:  1994-12-01       Impact factor: 3.857

7.  Identification of a new inborn error in bile acid synthesis: mutation of the oxysterol 7alpha-hydroxylase gene causes severe neonatal liver disease.

Authors:  K D Setchell; M Schwarz; N C O'Connell; E G Lund; D L Davis; R Lathe; H R Thompson; R Weslie Tyson; R J Sokol; D W Russell
Journal:  J Clin Invest       Date:  1998-11-01       Impact factor: 14.808

8.  Demonstration of 26-hydroxylation of C27-steroids in human skin fibroblasts, and a deficiency of this activity in cerebrotendinous xanthomatosis.

Authors:  S Skrede; I Björkhem; E A Kvittingen; M S Buchmann; S O Lie; C East; S Grundy
Journal:  J Clin Invest       Date:  1986-09       Impact factor: 14.808

9.  Kinetic analysis of LDL oxidation in IHD and IHD risk subjects in Indian population.

Authors:  Yashika Gupta; V Mallika; D K Srivastava
Journal:  Indian J Clin Biochem       Date:  2003-01

10.  Cholesterol metabolism. Effect of 26-thiacholesterol and 26-aminocholesterol, analogues of 26-hydroxycholesterol, on cholesterol synthesis and low-density-lipoprotein-receptor binding.

Authors:  E Miao; S R Wilson; N B Javitt
Journal:  Biochem J       Date:  1988-11-01       Impact factor: 3.857
  10 in total

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