Literature DB >> 2178954

Metabolism of 3 beta-hydroxycholest-5-en-26-oic acid in hamsters.

Y Ayaki1, E Kok, N B Javitt.   

Abstract

Metabolism of 26-hydroxycholesterol to 3 beta-hydroxychol-5-en-24-oic acid and other C24-bile acids has been expected to occur by way of 3 beta-hydroxycholest-5-en-26-oic acid in studies in vitro. 3 beta-Hydroxycholest-5-en-26-oic acid was infused intravenously into bile fistula hamsters and the following C24-bile acids were identified: 3 beta-hydroxychol-5-en-24-oic acid, lithocholic acid, chenodeoxycholic acid, and a small amount of cholic acid.

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Year:  1990        PMID： 2178954     DOI： 10.1007/BF01951761

Source DB:  PubMed          Journal:  Experientia        ISSN： 0014-4754


  12 in total

1.  The in vitro production of 25- and 26-hydroxycholesterol and their in vivo metabolism.

Authors:  D S FREDRICKSON; K ONO
Journal:  Biochim Biophys Acta       Date:  1956-10

2.  Cholic acid synthesis from 26-hydroxycholesterol and 3-hydroxy-5-cholestenoic acid in the rabbit.

Authors:  Y Ayaki; E Kok; N B Javitt
Journal:  J Biol Chem       Date:  1989-03-05       Impact factor: 5.157

3.  Metabolic pathways of bile acid formation in the rat.

Authors:  N B Javitt; S Emerman
Journal:  Mt Sinai J Med       Date:  1970 Jul-Aug

4.  Metabolism of cholest-5-ene-3 beta, 26-diol in the rat and hamster.

Authors:  N Wachtel; S Emerman; N B Javitt
Journal:  J Biol Chem       Date:  1968-10-10       Impact factor: 5.157

5.  Metabolism of taurolithocholic acid in the hamster.

Authors:  S Emerman; N B Javitt
Journal:  J Biol Chem       Date:  1967-02-25       Impact factor: 5.157

6.  The formation of lithocholic acid, chenodeoxycholic acid and alpha- and beta-muricholic acids from cholesterol incubated with rat-liver mitochondria.

Authors:  K A Mitropoulos; N B Myant
Journal:  Biochem J       Date:  1967-05       Impact factor: 3.857

7.  Bile acid synthesis in man: metabolism of 7 -hydroxycholesterol- 14 C and 26-hydroxycholesterol- 3 H.

Authors:  K E Anderson; E Kok; N B Javitt
Journal:  J Clin Invest       Date:  1972-01       Impact factor: 14.808

8.  Bile acid synthesis. Metabolism of 3 beta-hydroxy-5-cholenoic acid to chenodeoxycholic acid.

Authors:  N B Javitt; E Kok; F Carubbi; T Blizzard; M Gut; C Y Byon
Journal:  J Biol Chem       Date:  1986-09-25       Impact factor: 5.157

9.  26-Hydroxycholesterol. Identification and quantitation in human serum.

Authors:  N B Javitt; E Kok; S Burstein; B Cohen; J Kutscher
Journal:  J Biol Chem       Date:  1981-12-25       Impact factor: 5.157

10.  Chenodeoxycholic acid synthesis in the hamster: a metabolic pathway via 3 beta, 7 alpha-dihydroxy-5-cholen-24-oic acid.

Authors:  B Kulkarni; N B Javitt
Journal:  Steroids       Date:  1982-11       Impact factor: 2.668
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