| Literature DB >> 7306953 |
M Y Ovelar, A Cardesa, U Mohr.
Abstract
Sprague-Dawley rats received subcutaneous injections of 2,6-dimethylnitrosomorpholine (2,6-DMNM) at 3 different dose levels (1/5, 1/10 or 1/20 LD50) once weekly for life. Up to a 100% rate of tumors of the esophagus was detected in animals which received 1/10 and 1/20 LD50. In addition to tumors of this organ, neoplasms developed at different rates in the lungs and in the liver.Entities:
Mesh：
Substances：
Year: 1981 PMID： 7306953 DOI： 10.1016/0304-3835(81)90143-9
Source DB: PubMed Journal: Cancer Lett ISSN： 0304-3835 Impact factor: 8.679