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Literature DB >> 730203

The effect of donor age on the in vitro life span of cultured human arterial smooth-muscle cells.

Abstract

The number of population doublings of cultured human arterial smooth-muscle cells decreased as a function of donor age (0.5 to 82 years). Cells from older donors also showed longer latent periods for outgrowth from explants. These results extend other comparable observations with human skin fibroblasts to another cell type, and may have relevance to the pathogenesis of atherosclerosis with aging in vivo.

Entities: Disease Species

Mesh：

Year: 1978 PMID： 730203 DOI： 10.1007/bf02616126

Source DB: PubMed Journal: In Vitro ISSN： 0073-5655

16 in total

1. The serial cultivation of human diploid cell strains.

Authors: L HAYFLICK; P S MOORHEAD
Journal: Exp Cell Res Date: 1961-12 Impact factor: 3.905

2. Tissue-specific differences in cultured human diploid fibroblasts.

Authors: E L Schneider; Y Mitsui; K S Au; S S Shorr
Journal: Exp Cell Res Date: 1977-08 Impact factor: 3.905

3. Lipoprotein uptake and metabolism by rat aortic smooth muscle cells in tissue culture.

Authors: E L Bierman; O Stein; Y Stein
Journal: Circ Res Date: 1974-07 Impact factor: 17.367

4. Symposium on in vitro studies related to atherogenesis. Life histories of hyperplastoid cell lines from aorta and skin.

Authors: G M Martin; C A Sprague
Journal: Exp Mol Pathol Date: 1973-04 Impact factor: 3.362

5. Latent period for outgrowth of human skin explants as a function of age.

Authors: H Waters; R L Walford
Journal: J Gerontol Date: 1970-10

6. Comparison of vascular smooth muscle cells from adult human, monkey and rabbit in primary culture and in subculture.

Authors: J H Chamley; G R Campbell; J D McConnell; U Gröschel-Stewart
Journal: Cell Tissue Res Date: 1977-02-14 Impact factor: 5.249

7. Long-term culture of human adult liver cells: morphological changes related to in vitro senescence and effect of donor's age on growth potential.

Authors: Y Le Guilly; M Simon; P Lenoir; M Bourel
Journal: Gerontologia Date: 1973

8. Diabetes mellitus and aging: diminished planting efficiency of cultured human fibroblasts.

Authors: S Goldstein; J W Littlefield; J S Soeldner
Journal: Proc Natl Acad Sci U S A Date: 1969-09 Impact factor: 11.205

9. The relationship between in vitro cellular aging and in vivo human age.

Authors: E L Schneider; Y Mitsui
Journal: Proc Natl Acad Sci U S A Date: 1976-10 Impact factor: 11.205

10. The smooth muscle cell. II. Growth of smooth muscle in culture and formation of elastic fibers.

Authors: R Ross
Journal: J Cell Biol Date: 1971-07 Impact factor: 10.539

20 in total

Review 1. Can ends justify the means?: telomeres and the mechanisms of replicative senescence and immortalization in mammalian cells.

Authors: J M Sedivy
Journal: Proc Natl Acad Sci U S A Date: 1998-08-04 Impact factor: 11.205

Review 2. Human replicative senescence. A molecular study.

Authors: P J Hensler; O M Pereira-Smith
Journal: Am J Pathol Date: 1995-07 Impact factor: 4.307

Review 3. Cell culture aging.

Authors: M Reff; E L Schneider
Journal: Mol Cell Biochem Date: 1981-05-26 Impact factor: 3.396

The effect of donor age on the in vitro life span of cultured human arterial smooth-muscle cells.

1. The serial cultivation of human diploid cell strains.

2. Tissue-specific differences in cultured human diploid fibroblasts.

3. Lipoprotein uptake and metabolism by rat aortic smooth muscle cells in tissue culture.

4. Symposium on in vitro studies related to atherogenesis. Life histories of hyperplastoid cell lines from aorta and skin.

5. Latent period for outgrowth of human skin explants as a function of age.

6. Comparison of vascular smooth muscle cells from adult human, monkey and rabbit in primary culture and in subculture.

7. Long-term culture of human adult liver cells: morphological changes related to in vitro senescence and effect of donor's age on growth potential.

8. Diabetes mellitus and aging: diminished planting efficiency of cultured human fibroblasts.

9. The relationship between in vitro cellular aging and in vivo human age.

10. The smooth muscle cell. II. Growth of smooth muscle in culture and formation of elastic fibers.

Review 1. Can ends justify the means?: telomeres and the mechanisms of replicative senescence and immortalization in mammalian cells.

Review 2. Human replicative senescence. A molecular study.

Review 3. Cell culture aging.

4. Organ culture of the Islets of Langerhans from young and senescent rats.

5. Human smooth muscle cells cultured from atherosclerotic plaques and uninvolved vessel wall.

6. Tissue culture in aging research: present status and prospects.

7. Telomere length and replicative aging in human vascular tissues.

8. Relationship between donor age and the replicative lifespan of human cells in culture: a reevaluation.

9. Some in-vitro comparisons of synovial cells dispersed by trypsin from rheumatoid and nonrheumatoid synovium.

10. Human arteries engineered in vitro.