Literature DB >> 7298086

Strong teratocarcinoma transplantation loci, Gt-1 and Gt-2, flank H-2.

A Shedlovsky, L J Clipson, J L VandeBerg, W F Dove.   

Abstract

Evidence is presented for the existence of two strong murine teratocarcinoma transplantation antigens (Gt) on the cell line PCC3. It is shown that the loci governing expression of these antigens are linked to the H-2 complex. These loci have been further mapped with respect to the brachyury marker (T) and H-2: Gt-1 lies 5 +/- 2 crossover units proximal to H-2 and 12 +/- 2 crossover units distal to T; Gt-2 lies 21 +/- 4 crossover units distal to H-2. It is possible that these strong transplantation antigens provide an embryonic analogue to the adult major histocompatibility system.

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Year:  1981        PMID: 7298086     DOI: 10.1007/bf00346022

Source DB:  PubMed          Journal:  Immunogenetics        ISSN: 0093-7711            Impact factor:   2.846


  18 in total

1.  Embryonal carcinoma antigen and the T/t locus of the mouse.

Authors:  R Kemler; C Babinet; H Condamine; G Gachelin; J L Guenet; F Jacob
Journal:  Proc Natl Acad Sci U S A       Date:  1976-11       Impact factor: 11.205

Review 2.  An analysis of the murine NK cell as to structure, function and biological relevance.

Authors:  R Kiessling; H Wigzell
Journal:  Immunol Rev       Date:  1979       Impact factor: 12.988

3.  Immune response of mice to Thy-1. 1 antigen: genetic control by alleles at the Ir-5 locus loosely linked to the H-2 complex.

Authors:  M Zaleski; J Klein
Journal:  J Immunol       Date:  1974-10       Impact factor: 5.422

4.  Cell surfaces and embryos: expression of the F9 teratocarcinoma antigen in T-region lethal, other lethal, and normal pre-implantation mouse embryos.

Authors:  R P Erickson; S E Lewis
Journal:  J Reprod Immunol       Date:  1980-12       Impact factor: 4.054

5.  Natural killer cells mediate lysis of embryonal carcinoma cells lacking MHC.

Authors:  P Stern; M Gidlund; A Orn; H Wigzell
Journal:  Nature       Date:  1980-05-29       Impact factor: 49.962

6.  Semisyngeneic hybrid resistance to murine teratocarcinoma cells.

Authors:  G A Bishop; W F Dove
Journal:  Immunogenetics       Date:  1980       Impact factor: 2.846

7.  The genetics of teratocarcinoma transplantation: tumor formation in allogeneic hosts by the embryonal carcinoma cell lines F9 and PCC3.

Authors:  P R Avner; W F Dove; P Dubois; J A Gaillard; J L Guénet; F Jacob; H Jakob; A Shedlovsky
Journal:  Immunogenetics       Date:  1978-12       Impact factor: 2.846

8.  Teratocarcinoma transplantation rejection loci: genetic localization of the Gt-1 locus on chromosome 17 and the expression of alternate alleles.

Authors:  A J Levine; A K Teresky
Journal:  Immunogenetics       Date:  1981       Impact factor: 2.846

9.  H-Y antigen: genetic control of the expression as detected by host-versus-graft popliteal lymph node enlargement assay maps between the T and H-2 complexes.

Authors:  J Králová; A Lengerová
Journal:  J Immunogenet       Date:  1979-12

10.  Cross-reactivity between H-2K and H-2D products. I. Evidence for extensive and reciprocal serological cross-reactivity.

Authors:  D B Murphy; D C Shrefler
Journal:  J Exp Med       Date:  1975-02-01       Impact factor: 14.307

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  11 in total

1.  Transfected H-2Kb gene as a cause of embryonal carcinoma cell rejection in vivo.

Authors:  B Mosinger; J Forejt
Journal:  Immunogenetics       Date:  1989       Impact factor: 2.846

2.  Overt expression of H-2 serotypes on EC cells is not necessary for host rejection.

Authors:  L J Maher; W F Dove
Journal:  Immunogenetics       Date:  1984       Impact factor: 2.846

3.  Male-specific transplantation antigen expression by XY teratocarcinomas PCC7 and 7'.

Authors:  L L Johnson; W F Dove
Journal:  Immunogenetics       Date:  1984       Impact factor: 2.846

Review 4.  H-2 haplotypes, genes, and antigens: second listing. I. Non-H-2 loci on chromosome 17.

Authors:  J Klein; F Figueroa; D Klein
Journal:  Immunogenetics       Date:  1982       Impact factor: 2.846

5.  Minor histocompatibility antigen expression on F9 embryonal carcinoma cells revealed by T-cell mediated responses.

Authors:  M C Simmler; P Avner; J P Levy
Journal:  Immunogenetics       Date:  1982       Impact factor: 2.846

6.  Teratocarcinoma transplantation rejection loci: genetic localization of the Gt-1 locus on chromosome 17 and the expression of alternate alleles.

Authors:  A J Levine; A K Teresky
Journal:  Immunogenetics       Date:  1981       Impact factor: 2.846

7.  Analysis of the xenogeneic T-cell response to murine H-2 negative embryonal carcinoma cells.

Authors:  R Aspinall; P L Stern
Journal:  Immunology       Date:  1985-03       Impact factor: 7.397

8.  Teratocarcinoma transplantation antigens are encoded in the H-2 region.

Authors:  L L Johnson; L J Clipson; W F Dove; J Feilbach; L J Maher; A Shedlovsky
Journal:  Immunogenetics       Date:  1983       Impact factor: 2.846

9.  Mice coisogenically immunized against H-2 class I antigens on transfected L cells reject transplanted embryonal carcinoma cells.

Authors:  A R Moser; L L Johnson; W F Dove
Journal:  Immunogenetics       Date:  1985       Impact factor: 2.846

10.  H-2 class I antigen expression on mouse teratocarcinoma cell lines.

Authors:  P Démant; M Oudshoorn-Snoek
Journal:  Immunogenetics       Date:  1985       Impact factor: 2.846

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