Literature DB >> 7297644

Increase in in vivo (3H) spiperone binding in the rat hippocampal formation and striatum after repeated treatment with haloperidol.

S Bischoff.   

Abstract

An increase in in vivo (3H) spiperone binding was observed in rat hippocampal formation and striatum after repeated treatment with haloperidol. This suggests that in hippocampus as well as in striatum prolonged blockade of dopaminergic transmission by a neuroleptic agent results in the development of a supersensitivity of the dopamine receptors.

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Year:  1981        PMID： 7297644     DOI： 10.1007/bf01971808

Source DB:  PubMed          Journal:  Experientia        ISSN： 0014-4754


  10 in total

1.  Biochemical evidence for a transmitter role of dopamine in the rat hippocampus.

Authors:  S Bischoff; B Scatton; J Korf
Journal:  Brain Res       Date:  1979-04-06       Impact factor: 3.252

2.  Efferents and afferents of the ventral tegmental-A10 region studied after local injection of [3H]leucine and horseradish peroxidase.

Authors:  H Simon; M Le Moal; A Calas
Journal:  Brain Res       Date:  1979-12-07       Impact factor: 3.252

3.  Differential changes in DOPAC levels in the hippocampal formation, septum and striatum of the rat induced by acute and repeated neuroleptic treatment.

Authors:  B Scatton
Journal:  Eur J Pharmacol       Date:  1981-05-22       Impact factor: 4.432

4.  Increased in vivo binding of 3H-pimozide in mouse striatum following repeated administration of haloperidol.

Authors:  J C Schwartz; M Baudry; M P Martres; J Costentin; P Protais
Journal:  Life Sci       Date:  1978-10-30       Impact factor: 5.037

5.  Antischizophrenic drugs: chronic treatment elevates dopamine receptor binding in brain.

Authors:  D R Burt; I Creese; S H Snyder
Journal:  Science       Date:  1977-04-15       Impact factor: 47.728

6.  Origin of dopaminergic innervation of the rat hippocampal formation.

Authors:  B Scatton; H Simon; M Le Moal; S Bischoff
Journal:  Neurosci Lett       Date:  1980-06       Impact factor: 3.046

7.  In vivo [3H]spiperone binding to the rat hippocampal formation: involvement of dopamine receptors.

Authors:  S Bischoff; H Bittiger; J Krauss
Journal:  Eur J Pharmacol       Date:  1980-12-05       Impact factor: 4.432

8.  The membrane potential of cat hippocampal neurons recorded in vivo displays four different reaction-mechanisms to iontophoretically applied transmitter agonists.

Authors:  P L Herrling
Journal:  Brain Res       Date:  1981-05-18       Impact factor: 3.252

9.  Apomorphine and glycoprotein synthesis in rat hippocampus.

Authors:  R Jork; G Grecksch; M Jirka; B Lössner; H Matthies
Journal:  Pharmacol Biochem Behav       Date:  1980-02       Impact factor: 3.533

10.  Dopamine metabolism, spiperone binding and adenylate cyclase activity in the adult rat hippocampus after ingrowth of dopaminergic neurones from embryonic implants.

Authors:  S Bischoff; B Scatton; J Korf
Journal:  Brain Res       Date:  1979-12-21       Impact factor: 3.252
  10 in total
  3 in total

1.  Correlations between different measures of antiserotonin activity of drugs. Study with neuroleptics and serotonin receptor blockers.

Authors:  R Ortmann; S Bischoff; E Radeke; O Buech; A Delini-Stula
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1982-12       Impact factor: 3.000

2.  Modulation of dopaminergic transmission by alpha-noradrenergic agonists and antagonists: evidence for antidopaminergic properties of some alpha antagonists.

Authors:  P C Waldmeier; R Ortmann; S Bischoff
Journal:  Experientia       Date:  1982-10-15

3.  Role of dopamine receptors in the modulation of acetylcholine release in the rabbit hippocampus.

Authors:  H Strittmatter; R Jackisch; G Hertting
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1982-12       Impact factor: 3.000
  3 in total

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