Vitiliginous chorioretinitis.

Eleven patients had a syndrome characterized by (1) onset, in apparently healthy patients, usually women in the third to sixth decade of life, of floaters and photopsia, blurred vision, and often followed later by night blindness and color blindness, (2) vitreous inflammation, (3) multifocal patches of depigmentation of the choroid and the pigment epithelium in the postequatorial fundi, (4) varying degrees of retinal edema and papilledema, narrowing of the retinal vessels, and mild optic atrophy, (5) moderate to severe electroretinographic findings, and (6) a variable rate of progression and severity, but with a tendency toward stabilization and preservation of good central vision in at least one eye. "Vitiliginous chorioretinitis" was chosen as the name for this syndrome because of the similarity of the appearance and evolution of the patches of choroidal depigmentation to that occurring in the skin of patients with vitiligo.