| Literature DB >> 31748943 |
Dominika Pohlmann1, Sibylle Winterhalter2, Uwe Pleyer2.
Abstract
The white dot syndromes include a group of diseases which are characterized by multiple yellowish-white foci in the outer retina, retinal pigment epithelium, and choroid. For clinicians and researchers alike they present significant diagnostic and therapeutic challenges. White dot syndromes include primary inflammatory choriocapillaropathies, such as acute posterior multifocal placoid pigment epitheliopathy (APMPPE)/acute multifocal ischemic choriocapillaropathy (AMIC), multiple evanescent white dot syndrome (MEWDS)/acute idiopathic blind spot enlargement (AIBSE), multifocal choroiditis (MFC), punctate inner choroidopathy (PIC), serpiginous choroiditis (SC), acute zonal occult outer retinopathy (AZOOR), and acute macular neuroretinopathy (AMN). Among the primary stromal choroiditis is birdshot retinochoroidopathy (BSRC); however, the pathogenesis of these disorders is largely unknown. Immunological reactions to previous viral infections with a genetic disposition seem to be a common denominator.Entities:
Keywords: Autoimmune disease; Choroid; Genetic predisposition; Infection; Retinal pigment epithelium
Mesh:
Year: 2019 PMID: 31748943 DOI: 10.1007/s00347-019-01012-5
Source DB: PubMed Journal: Ophthalmologe ISSN: 0941-293X Impact factor: 1.059