Literature DB >> 7293670

Biomechanical changes in connective tissues induced by experimental diabetes.

T T Andreassen, K Seyer-Hansen, H Oxlund.   

Abstract

The biomechanical properties of skin and aorta were studied in rats with experimental (streptozotocin) diabetes. After 30 days of diabetes the collagen content of the skin was diminished by 30%. By biomechanical testing collagen from diabetic rats was found to exhibit increased stiffness and strength: maximal stiffness was increased by 20% and the strain at maximum stress was decreased by 10%. Insulin treatment prevented all changes. No differences were found between aortic specimens from diabetic and normal rats.

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Year:  1981        PMID： 7293670     DOI： 10.1530/acta.0.0980432

Source DB:  PubMed          Journal:  Acta Endocrinol (Copenh)        ISSN： 0001-5598


  7 in total

1.  Beneficial effect of myricetin on renal functions in streptozotocin-induced diabetes.

Authors:  Filiz Ozcan; Asli Ozmen; Bahar Akkaya; Yakup Aliciguzel; Mutay Aslan
Journal:  Clin Exp Med       Date:  2011-11-15       Impact factor: 3.984

2.  The compressive, shear, biochemical, and histological characteristics of diabetic and non-diabetic plantar skin are minimally different.

Authors:  Lynda Brady; Shruti Pai; Joseph M Iaquinto; Yak-Nam Wang; William R Ledoux
Journal:  J Biomech       Date:  2021-10-07       Impact factor: 2.712

3.  Thermal stability of collagen in relation to non-enzymatic glycosylation and browning in vitro.

Authors:  T T Andreassen; H Oxlund
Journal:  Diabetologia       Date:  1985-09       Impact factor: 10.122

4.  The thermal stability of collagen in diabetic rats: correlation with severity of diabetes and non-enzymatic glycosylation.

Authors:  D K Yue; S McLennan; L Delbridge; D J Handelsman; T Reeve; J R Turtle
Journal:  Diabetologia       Date:  1983-04       Impact factor: 10.122

5.  The contribution of a directional preference of stiffness to the efficacy of prophylactic sacral dressings in protecting healthy and diabetic tissues from pressure injury: computational modelling studies.

Authors:  Ayelet Levy; Dafna Schwartz; Amit Gefen
Journal:  Int Wound J       Date:  2017-09-27       Impact factor: 3.315

6.  Effects of photochemical riboflavin-mediated crosslinks on the physical properties of collagen constructs and fibrils.

Authors:  Harvey Rich; Marianne Odlyha; Umber Cheema; Vivek Mudera; Laurent Bozec
Journal:  J Mater Sci Mater Med       Date:  2013-09-05       Impact factor: 3.896

7.  Localized micro- and nano-scale remodelling in the diabetic aorta.

Authors:  R Akhtar; J K Cruickshank; X Zhao; L A Walton; N J Gardiner; S D Barrett; H K Graham; B Derby; M J Sherratt
Journal:  Acta Biomater       Date:  2014-07-09       Impact factor: 8.947
  7 in total

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