Literature DB >> 7287580

New anthracyclines, feudomycins, produced by the mutant from Streptomyces coeruleorubidus ME130-A4.

T Oki, Y Matsuzawa, K Kiyoshima, A Yoshimoto, H Naganawa, T Takeuchi, H Umezawa.   

Abstract

Various blocked mutants were isolated from Streptomyces coeruleorubidus ME130-A4 by NTG and UV treatments. Among them, mutant strain 4N-140 produced new anthracycline feudomycins A and B having new aglycones in which the side chain at C-9 position of daunomycinone was ethyl and acetonyl, respectively. New aglycones feudomycinones C and D having methyl at C-9 and additional groups at C-10 of daunomycinone were also isolated from this strain.

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Year:  1981        PMID: 7287580     DOI: 10.7164/antibiotics.34.783

Source DB:  PubMed          Journal:  J Antibiot (Tokyo)        ISSN: 0021-8820            Impact factor:   2.649


  6 in total

1.  A silent ABC transporter isolated from Streptomyces rochei F20 induces multidrug resistance.

Authors:  M A Fernández-Moreno; L Carbó; T Cuesta; C Vallín; F Malpartida
Journal:  J Bacteriol       Date:  1998-08       Impact factor: 3.490

Review 2.  Streptomycetes producing daunomycin and related compounds: do we know enough about them after 25 years?

Authors:  J Huk; M Blumauerova
Journal:  Folia Microbiol (Praha)       Date:  1989       Impact factor: 2.099

3.  Antifungal activities of actinomycete strains associated with high-altitude sagebrush rhizosphere.

Authors:  A E Jiménez-Esquilín; T M Roane
Journal:  J Ind Microbiol Biotechnol       Date:  2005-09-29       Impact factor: 3.346

4.  The level of a transcript required for production of a Streptomyces coelicolor antibiotic is conditionally dependent on a tRNA gene.

Authors:  E P Guthrie; K F Chater
Journal:  J Bacteriol       Date:  1990-11       Impact factor: 3.490

5.  abaA, a new pleiotropic regulatory locus for antibiotic production in Streptomyces coelicolor.

Authors:  M A Fernández-Moreno; A J Martín-Triana; E Martínez; J Niemi; H M Kieser; D A Hopwood; F Malpartida
Journal:  J Bacteriol       Date:  1992-05       Impact factor: 3.490

6.  In vivo and in vitro bioconversion of epsilon-rhodomycinone glycoside to doxorubicin: functions of DauP, DauK, and DoxA.

Authors:  M L Dickens; N D Priestley; W R Strohl
Journal:  J Bacteriol       Date:  1997-04       Impact factor: 3.490

  6 in total

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