Literature DB >> 2691361

Streptomycetes producing daunomycin and related compounds: do we know enough about them after 25 years?

J Huk1, M Blumauerova.   

Abstract

The growing need of highly potent anticancer agents has stimulated the investigation of streptomycetes producing daunomycin-type anthracyclines. This review compares the features of production strains and their mutants and emphasizes the necessity of application of biochemical and biophysical analytical methods for better understanding these microorganisms and, above all, their further improving and practical usage.

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Year:  1989        PMID： 2691361     DOI： 10.1007/bf02814475

Source DB:  PubMed          Journal:  Folia Microbiol (Praha)        ISSN： 0015-5632            Impact factor:   2.099


  75 in total

1.  'DAUNOMYCIN', A NEW ANTIBIOTIC OF THE RHODOMYCIN GROUP.

Authors:  A DIMARCO; M GAETANI; P OREZZI; B M SCARPINATO; R SILVESTRINI; M SOLDATI; T DASDIA; L VALENTINI
Journal:  Nature       Date:  1964-02-15       Impact factor: 49.962

2.  Molecular level studies with anthracyclines.

Authors:  E Eckle; E Kiefer; G Lauser; J J Stezowski
Journal:  Drugs Exp Clin Res       Date:  1985

3.  Inhibition of the biosynthesis of leucomycin, a macrolide antibiotic, by cerulenin.

Authors:  S Omura; H Takeshima
Journal:  J Biochem       Date:  1974-01       Impact factor: 3.387

4.  Preparation of labeled aklanonic acid and its bioconversion to anthracyclinones by mutants of Streptomyces griseus.

Authors:  K Eckardt; G Schumann; U Gräfe; W Ihn; C Wagner; W F Fleck; H Thrum
Journal:  J Antibiot (Tokyo)       Date:  1985-08       Impact factor: 2.649

Review 5.  Interactions of antineoplastic antibiotics and DNA.

Authors:  G F Gause; Y V Dudnik
Journal:  Antibiot Chemother (1971)       Date:  1980

6.  Leukaemomycin, in antibiotic with antitumor activity. II. Isolation and identification.

Authors:  D Strauss; W Fleck
Journal:  Z Allg Mikrobiol       Date:  1975

7.  The differential effects produced by daunomycin and adriamycin on RNA, polynucleotides, single stranded, supercoiled DNA, and nucleosomes.

Authors:  L F Pearlman; H Simpkins
Journal:  Biochem Biophys Res Commun       Date:  1985-09-16       Impact factor: 3.575

8.  New anthracycline glycosides from Micromonospora. I. Description of the producing strain.

Authors:  A Grein; S Merli; C Spalla
Journal:  J Antibiot (Tokyo)       Date:  1980-12       Impact factor: 2.649

Review 9.  The effectiveness of the anthracycline analog 4'-epidoxorubicin in the treatment of experimental tumors: a review.

Authors:  A Goldin; J M Venditti; R Geran
Journal:  Invest New Drugs       Date:  1985       Impact factor: 3.850

10.  Clinical toxicity of 4'-epi-doxorubicin (epirubicin).

Authors:  F Ganzina; N Di Pietro; O Magni
Journal:  Tumori       Date:  1985-06-30
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