Literature DB >> 7284699

The effects of intracerebroventricular cycloheximide on protein synthesis and fever in rabbits.

W I Cranston, V N Gourine, Y Townsend.   

Abstract

Cycloheximide (40 micrograms) intracerebroventricularly (i.c.v.) had no effect on thermoregulation against cold, but reduced fever due to an i.c.v. injection of leucocyte pyrogen (LP) by 25%, and reduced incorporation of radioactive leucine into hypothalamic protein by 94%.

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Year:  1981        PMID： 7284699      PMCID： PMC2071853          DOI： 10.1111/j.1476-5381.1981.tb16763.x

Source DB:  PubMed          Journal:  Br J Pharmacol        ISSN： 0007-1188            Impact factor:   8.739


  6 in total

1.  Central mechanisms of fever.

Authors:  W I Cranston
Journal:  Fed Proc       Date:  1979-01

2.  The prevention by inhibitors of brain proptein synthesis of the hyperactivity and hyperpyrexia produced in rats by monoamine oxidase inhibition and the administration of L-tryptophan or 5-methoxy-N,N-dimethyltryptamine.

Authors:  D G Grahame-Smith
Journal:  J Neurochem       Date:  1972-10       Impact factor: 5.372

3.  The central respiratory stimulant action of salicylates.

Authors:  I R Cameron; S J Semple
Journal:  Clin Sci       Date:  1968-10       Impact factor: 6.124

4.  Effect of cycloheximide on temperature regulation in rats.

Authors:  C C Barney; M J Katovich; M J Fregly
Journal:  Brain Res Bull       Date:  1979 May-Jun       Impact factor: 4.077

5.  Suppression of fever in rabbits by a protein synthesis inhibitor, anisomycin.

Authors:  W I Cranston; R F Hellon; Y Townsend
Journal:  J Physiol       Date:  1980-08       Impact factor: 5.182

6.  Mechanism of fever induction in rabbits.

Authors:  R Siegert; W K Philipp-Dormston; K Radsak; H Menzel
Journal:  Infect Immun       Date:  1976-11       Impact factor: 3.441
  6 in total
  3 in total

1.  Inhibition, by trichothecene antibiotics, of brain protein synthesis and fever in rabbits.

Authors:  M Cannon; W I Cranston; R F Hellon; Y Townsend
Journal:  J Physiol       Date:  1982-01       Impact factor: 5.182

2.  Further observations on the suppression of fever in rabbits by intracerebral action of anisomycin.

Authors:  W I Cranston; R F Hellon; Y Townsend
Journal:  J Physiol       Date:  1982-01       Impact factor: 5.182

3.  Suppression of antipyretic response in rabbits by intraventricular protein synthesis inhibitor, anisomycin.

Authors:  A Morimoto; T Nakamori; T Watanabe; Y Sakata; N Murakami
Journal:  Pflugers Arch       Date:  1987-04       Impact factor: 3.657
  3 in total

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