Literature DB >> 3495780

Suppression of antipyretic response in rabbits by intraventricular protein synthesis inhibitor, anisomycin.

A Morimoto, T Nakamori, T Watanabe, Y Sakata, N Murakami.   

Abstract

Fevers induced by intravenous injection of endogenous pyrogen (EP) and intraventricular prostaglandin E2 (PGE2) were significantly prolonged when protein synthesis inhibitor, anisomycin was administrated intraventricularly 30 min before or 1 hr after injection of EP or PGE2. The present results show that protein synthesis in the central nervous system is involved in the development of antipyresis.

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Year:  1987        PMID： 3495780     DOI： 10.1007/BF00581138

Source DB:  PubMed          Journal:  Pflugers Arch        ISSN： 0031-6768            Impact factor:   3.657


  9 in total

1.  Pathogenesis of fever.

Authors:  E ATKINS
Journal:  Physiol Rev       Date:  1960-07       Impact factor: 37.312

2.  Inhibition, by trichothecene antibiotics, of brain protein synthesis and fever in rabbits.

Authors:  M Cannon; W I Cranston; R F Hellon; Y Townsend
Journal:  J Physiol       Date:  1982-01       Impact factor: 5.182

3.  Further observations on the suppression of fever in rabbits by intracerebral action of anisomycin.

Authors:  W I Cranston; R F Hellon; Y Townsend
Journal:  J Physiol       Date:  1982-01       Impact factor: 5.182

4.  Suppression of fever in rabbits by a protein synthesis inhibitor, anisomycin.

Authors:  W I Cranston; R F Hellon; Y Townsend
Journal:  J Physiol       Date:  1980-08       Impact factor: 5.182

5.  The effects of intracerebroventricular cycloheximide on protein synthesis and fever in rabbits.

Authors:  W I Cranston; V N Gourine; Y Townsend
Journal:  Br J Pharmacol       Date:  1981-05       Impact factor: 8.739

6.  Fever produced by intrahypothalamic pyrogen: effect of protein synthesis inhibition by anisomycin.

Authors:  W D Ruwe; R D Myers
Journal:  Brain Res Bull       Date:  1979 Nov-Dec       Impact factor: 4.077

7.  Evidence supporting a role for endogenous vasopressin in natural suppression of fever in the sheep.

Authors:  K E Cooper; N W Kasting; K Lederis; W L Veale
Journal:  J Physiol       Date:  1979-10       Impact factor: 5.182

8.  Rat endogenous pyrogen and fever.

Authors:  A Morimoto; T Watanabe; T Ono; Y Sakata; N Murakami
Journal:  Am J Physiol       Date:  1986-05

9.  Effects on body temperature of prostaglandins of the A, E and F series on injection into the third ventricle of unanaesthetized cats and rabbits.

Authors:  A S Milton; S Wendlandt
Journal:  J Physiol       Date:  1971-10       Impact factor: 5.182
  9 in total

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