Literature DB >> 7272645

Growth hormone and other responses to clonidine in patients with endogenous depression.

S A Checkley, A P Slade, E Shur.   

Abstract

The growth hormone response to clonidine was significantly less in 10 drug-free patients with endogenous depression than in 10 normal subjects who were individually matched with the patients for age and sex. The hypotensive and sedative effects of clonidine in the two groups were similar. The findings may indicate a defect at central alpha adrenoceptors at least in neuro-endocrine systems.

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Year:  1981        PMID： 7272645     DOI： 10.1192/bjp.138.1.51

Source DB:  PubMed          Journal:  Br J Psychiatry        ISSN： 0007-1250            Impact factor:   9.319


  18 in total

Review 1.  The neuroendocrine approach to psychiatric disorders: a critical appraisal.

Authors:  E E Müller
Journal:  J Neural Transm Gen Sect       Date:  1990

2.  The effect of clonidine on plasma MHPG: evidence against tonic alpha 2-adrenoceptor control of noradrenergic function.

Authors:  D J Nutt; S G Molyneux
Journal:  Psychopharmacology (Berl)       Date:  1986       Impact factor: 4.530

3.  Effects of electroconvulsive therapy and desipramine on neuroendocrine responses to the clonidine challenge test.

Authors:  M Coote; A Wilkins; E S Werstiuk; M Steiner
Journal:  J Psychiatry Neurosci       Date:  1998-05       Impact factor: 6.186

4.  Effect of lithium treatment on the GH-clonidine test in affective disorders.

Authors:  F Brambilla; M Catalano; A Lucca; E Smeraldi
Journal:  Eur J Clin Pharmacol       Date:  1988       Impact factor: 2.953

5.  Serotonergic influence on the growth hormone response to clonidine in rat.

Authors:  B Söderpalm; L Andersson; M Carlsson; K Modigh; E Eriksson
Journal:  J Neural Transm       Date:  1987       Impact factor: 3.575

Review 6.  G protein-coupled receptors in major psychiatric disorders.

Authors:  Lisa A Catapano; Husseini K Manji
Journal:  Biochim Biophys Acta       Date:  2006-10-03

Review 7.  Can drugs cause depression? A review of the evidence.

Authors:  S B Patten; E J Love
Journal:  J Psychiatry Neurosci       Date:  1993-05       Impact factor: 6.186

8.  Changes in noradrenergic neuroendocrine responses following repeated seizures and the mechanism of action of ECT.

Authors:  J R McWilliam; B S Meldrum; S A Checkley
Journal:  Psychopharmacology (Berl)       Date:  1982       Impact factor: 4.530

9.  Up- and down- regulation of central postsynaptic alpha 2 receptors reflected in the growth hormone response to clonidine in reserpine-pretreated rats.

Authors:  E Eriksson; S Edén; K Modigh
Journal:  Psychopharmacology (Berl)       Date:  1982       Impact factor: 4.530

10.  Hormonal responses to clonidine and urinary MHPG in delusional and nondelusional melancholic patients: a placebo-controlled study.

Authors:  L Lykouras; M Markianos; J Hatzimanolis; D Malliaras; C Stefanis
Journal:  Eur Arch Psychiatry Clin Neurosci       Date:  1991       Impact factor: 5.270
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