Literature DB >> 3035083

Serotonergic influence on the growth hormone response to clonidine in rat.

B Söderpalm, L Andersson, M Carlsson, K Modigh, E Eriksson.   

Abstract

Administration of the alpha 2-adrenoceptor agonist clonidine induces growth hormone (GH) release in rat and man. In the present study it is shown that the GH response to clonidine is weaker in rats exposed to depletion of both noradrenaline and serotonin (by means of reserpine or the combined treatment of FLA-63 and PCPA) than in animals exposed to noradrenaline depletion (by means of FLA-63) only. The possibility that an impaired serotonergic neurotransmission contributes to the blunted GH responses to clonidine observed in patients suffering from endogenous depression is discussed.

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Year:  1987        PMID： 3035083     DOI： 10.1007/BF01244101

Source DB:  PubMed          Journal:  J Neural Transm            Impact factor:   3.575


  34 in total

1.  Evidence for noradrenergic involvement in episodic prolactin and growth hormone release in ovariectomized rats.

Authors:  A Negro-Vilar; S R Ojeda; J P Advis; S M McCann
Journal:  Endocrinology       Date:  1979-07       Impact factor: 4.736

2.  Effects of apomorphine and clonidine on rat plasma growth hormone after pretreatment with reserpine and electroconvulsive shocks.

Authors:  S Edén; K Modigh
Journal:  Brain Res       Date:  1977-07-01       Impact factor: 3.252

3.  The secretory pattern of growth hormone. An experimental study in the rat.

Authors:  S Edén
Journal:  Acta Physiol Scand Suppl       Date:  1978

4.  Adrenergic and serotoninergic control of growth hormone secretion in adult male rats.

Authors:  R Collu; F Fraschini; P Visconti; L Martini
Journal:  Endocrinology       Date:  1972-05       Impact factor: 4.736

5.  Differential effects of pharmacological manipulations of central alpha 1- and alpha 2-adrenergic receptors on the secretion of thyrotropin and growth hormone in male rats.

Authors:  L Krulich; M A Mayfield; M K Steele; B A McMillen; S M McCann; J I Koenig
Journal:  Endocrinology       Date:  1982-03       Impact factor: 4.736

6.  Evidence for a growth hormone releasing factor mediating alpha-adrenergic influence on growth hormone secretion in the rat.

Authors:  S Eden; E Eriksson; J B Martin; K Modigh
Journal:  Neuroendocrinology       Date:  1981-07       Impact factor: 4.914

7.  Effect of clonidine on growth hormone release in psychiatric patients and controls.

Authors:  N Matussek; M Ackenheil; H Hippius; F Müller; H T Schröder; H Schultes; B Wasilewski
Journal:  Psychiatry Res       Date:  1980-03       Impact factor: 3.222

8.  Central catecholamine depletion: effects on physiological growth hormone and prolactin secretion.

Authors:  J O Willoughby; T A Day
Journal:  Neuroendocrinology       Date:  1981-02       Impact factor: 4.914

9.  Cholinergic mediation of growth hormone secretion elicited by arginine, clonidine, and physical exercise in man.

Authors:  F F Casanueva; L Villanueva; J A Cabranes; J Cabezas-Cerrato; A Fernandez-Cruz
Journal:  J Clin Endocrinol Metab       Date:  1984-09       Impact factor: 5.958

10.  Effect of clonidine on growth hormone, prolactin, luteinizing hormone, follicle-stimulating hormone, and thyroid-stimulating hormone in the serum of normal men.

Authors:  S Lal; G Tolis; S B Martin; G M Brown; H Guyda
Journal:  J Clin Endocrinol Metab       Date:  1975-11       Impact factor: 5.958
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  2 in total

1.  Effects of alpha 2- and beta-adrenoceptor agonists on growth hormone secretion following lesion of the noradrenergic system of the rat.

Authors:  A Jaffer; W M Daniels; V A Russell; J J Taljaard
Journal:  Neurochem Res       Date:  1992-12       Impact factor: 3.996

Review 2.  The effects of neutrophil-generated hypochlorous acid and other hypohalous acids on host and pathogens.

Authors:  Agnes Ulfig; Lars I Leichert
Journal:  Cell Mol Life Sci       Date:  2020-07-13       Impact factor: 9.261
  2 in total

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