Literature DB >> 7271275

Comparative pharmacokinetics of cyclacillin and amoxicillin in infants and children.

C M Ginsburg, G H McCracken, T C Zweighaft, J C Clahsen.   

Abstract

Concentrations of cyclacillin in serum over a 6-h period were similar in fasted and milk-fed infants who received 25-mg/kg doses of cyclacillin suspension. Measured by the concentration in serum after oral administration of 15-mg/kg doses, cyclacillin was absorbed more rapidly, reached larger concentrations, and was cleared more promptly than was amoxicillin.

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Year:  1981        PMID: 7271275      PMCID: PMC181615          DOI: 10.1128/AAC.19.6.1086

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN: 0066-4804            Impact factor:   5.191


  5 in total

1.  Double-blind clinical trials of oral cyclacillin and ampicillin.

Authors:  J A Gold; C P Hegarty; M W Deitch; B R Walker
Journal:  Antimicrob Agents Chemother       Date:  1979-01       Impact factor: 5.191

2.  Serum and urinary concentrations of cyclacillin in humans.

Authors:  C G Hertz
Journal:  Antimicrob Agents Chemother       Date:  1973-09       Impact factor: 5.191

3.  Pharmacological and in vitro evaluation of cyclacillin: assessment as potential single-dose therapy for treatment of Neisseria gonorrhoeae infection.

Authors:  K F Wagner; A D Blair; G W Counts; K K Holmes
Journal:  Antimicrob Agents Chemother       Date:  1980-01       Impact factor: 5.191

4.  Microbioassay of antimicrobial agents.

Authors:  H J Simon; E J Yin
Journal:  Appl Microbiol       Date:  1970-04

5.  Comparative therapeutic and pharmacological evaluation of amoxicillin and ampicillin plus probenecid for the treatment of gonorrhea.

Authors:  W W Karney; M Turck; K K Holmes
Journal:  Antimicrob Agents Chemother       Date:  1974-02       Impact factor: 5.191

  5 in total
  3 in total

Review 1.  New formulations of amoxicillin/clavulanic acid: a pharmacokinetic and pharmacodynamic review.

Authors:  Amparo Sánchez Navarro
Journal:  Clin Pharmacokinet       Date:  2005       Impact factor: 6.447

2.  The "new" ampicillins: who needs them? Committee on Infectious Diseases and Immunization, Canadian Paediatric Society.

Authors: 
Journal:  Can Med Assoc J       Date:  1984-11-15       Impact factor: 8.262

3.  A comparison of the pharmacokinetics of bacampicillin, ampicillin, amoxicillin, and cyclacillin: oral administration in infants and children.

Authors:  G M McCracken
Journal:  Bull N Y Acad Med       Date:  1983-06
  3 in total

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