Literature DB >> 371540

Double-blind clinical trials of oral cyclacillin and ampicillin.

J A Gold, C P Hegarty, M W Deitch, B R Walker.   

Abstract

A double-blind study was performed to compare the clinical response and the incidence of side effects in 2,581 patients administered ampicillin or cyclacillin for infections of the genitourinary or respiratory tract, infections of the skin and soft tissues, or for otitis media. There was no significant difference in clinical response and bacterial eradication. All side effects, including diarrhea and skin rash, were approximately twice as frequent in patients treated with ampicillin.

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Year:  1979        PMID： 371540      PMCID： PMC352600          DOI： 10.1128/AAC.15.1.55

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  10 in total

1.  COMPARISON OF AMPICILLIN AND CHLORAMPHENICOL IN TREATMENT OF PARATYPHOID FEVER.

Authors:  R A SLEET; G SANGSTER; J M MURDOCH
Journal:  Br Med J       Date:  1964-01-18

2.  Hypersensitivity reactions to ampicillin in cytomegalovirus mononucleosis.

Authors:  E Klemola
Journal:  Scand J Infect Dis       Date:  1970

3.  Hypersensitivity reactions to antibacterial drugs in infectious mononucleosis.

Authors:  H Pullen; N Wright; J M Murdoch
Journal:  Lancet       Date:  1967-12-02       Impact factor: 79.321

4.  Adverse effects of orally administered ampicillin.

Authors:  J W Bass; D M Crowley; R W Steele; F S Young; L B Harden
Journal:  J Pediatr       Date:  1973-07       Impact factor: 4.406

5.  Ampicillin hypersensitivity in lymphatic leukaemia.

Authors:  S J Cameron; J Richmond
Journal:  Scott Med J       Date:  1971-10       Impact factor: 0.729

6.  Incidence of diarrhea in the treatment of genitourinary tract infections with ampicillin.

Authors:  T M Horrax
Journal:  Conn Med       Date:  1971-05

7.  The Aberdeen typhoid outbreak of 1964.

Authors:  W Walker
Journal:  Scott Med J       Date:  1965-12       Impact factor: 0.729

8.  [Effects and side-effects of ampicillin versus ciclacillin in a double blind randomized trial (author's transl)].

Authors:  P Rüefli
Journal:  Schweiz Rundsch Med Prax       Date:  1976-09-14

9.  Serum and urinary concentrations of cyclacillin in humans.

Authors:  C G Hertz
Journal:  Antimicrob Agents Chemother       Date:  1973-09       Impact factor: 5.191

10.  Incidence of antibiotic-related diarrhoea and pseudomembranous colitis: a prospective study of lincomycin, clindamycin and ampicillin.

Authors:  M B Robertson; K J Breen; P V Desmond; M L Mashford; A M McHugh
Journal:  Med J Aust       Date:  1977-02-19       Impact factor: 7.738
  10 in total
  5 in total

1.  Ampicillin and alternatives.

Authors:  A Dyas; R Wise
Journal:  Br Med J (Clin Res Ed)       Date:  1983-02-19

2.  The "new" ampicillins: who needs them? Committee on Infectious Diseases and Immunization, Canadian Paediatric Society.

Authors: 
Journal:  Can Med Assoc J       Date:  1984-11-15       Impact factor: 8.262

3.  Comparison of cyclacillin and amoxicillin for therapy for acute maxillary sinusitis.

Authors:  W M Scheld; A Sydnor; B Farr; J C Gratz; J M Gwaltney
Journal:  Antimicrob Agents Chemother       Date:  1986-09       Impact factor: 5.191

4.  Comparative pharmacokinetics of cyclacillin and amoxicillin in infants and children.

Authors:  C M Ginsburg; G H McCracken; T C Zweighaft; J C Clahsen
Journal:  Antimicrob Agents Chemother       Date:  1981-06       Impact factor: 5.191

5.  Pharmacological and in vitro evaluation of cyclacillin: assessment as potential single-dose therapy for treatment of Neisseria gonorrhoeae infection.

Authors:  K F Wagner; A D Blair; G W Counts; K K Holmes
Journal:  Antimicrob Agents Chemother       Date:  1980-01       Impact factor: 5.191
  5 in total

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