Literature DB >> 7270336

Platelet-tissue interaction: role of platelet-activating factor (PAF-acether).

B B Vargaftig, M Chignard, J Lefort, J Benveniste.   

Abstract

The platelet-activating factor, or PAF-acether, is a phospholipid derivative that is a potent aggregating agent. It is formed by platelets themselves and also by basophils, neutrophils, monocytes and macrophages including alveolar macrophages. A role for PAF-acether during inflammation is envisaged since its intravenous administration induces hypotension, thrombocytopenia and bronchoconstriction in anaesthetized guinea-pigs. It is hypothesized that platelets, which contain and synthetize many pro-inflammatory substances, play a primary role in some pathological states.

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Year:  1980        PMID： 7270336     DOI： 10.1007/BF02024151

Source DB:  PubMed          Journal:  Agents Actions        ISSN： 0065-4299


  20 in total

1.  Inflammation and the inflammatory mechanisms.

Authors:  N JANCSO
Journal:  J Pharm Pharmacol       Date:  1961-10       Impact factor: 3.765

2.  Platelets and inflammation.

Authors:  B B Vargaftig
Journal:  Agents Actions Suppl       Date:  1977

3.  The role of platelet-activating factor in platelet aggregation.

Authors:  M Chignard; J P Le Couedic; M Tence; B B Vargaftig; J Benveniste
Journal:  Nature       Date:  1979-06-28       Impact factor: 49.962

Review 4.  Platelet-activating factor.

Authors:  J Benveniste; J Camussi; J Polonsky
Journal:  Monogr Allergy       Date:  1977

5.  The release of a platelet-activating factor by stimulated rabbit neutrophils.

Authors:  J M Lynch; G Z Lotner; S J Betz; P M Henson
Journal:  J Immunol       Date:  1979-09       Impact factor: 5.422

6.  Blood platelets and the inflammatory process.

Authors:  M J Silver; J B Smith; C M Ingerman
Journal:  Agents Actions       Date:  1974-10

7.  Platelet-activating factor, a new mediator of anaphylaxis and immune complex deposition from rabbit and human basophils.

Authors:  J Benveniste
Journal:  Nature       Date:  1974-06-07       Impact factor: 49.962

8.  Platelet-activating factor induces a platelet-dependent bronchoconstriction unrelated to the formation of prostaglandin derivatives.

Authors:  B B Vargaftig; J Lefort; M Chignard; J Benveniste
Journal:  Eur J Pharmacol       Date:  1980-07-25       Impact factor: 4.432

9.  Platelet activating factor (PAF-acether): total synthesis of 1-O-octadecyl 2-O-acetyl sn-glycero-3-phosphoryl choline.

Authors:  J J Godfroid; F Heymans; E Michel; C Redeuilh; E Steiner; J Benveniste
Journal:  FEBS Lett       Date:  1980-07-28       Impact factor: 4.124

10.  Platelet-activating factor and macrophages. I. Evidence for the release from rat and mouse peritoneal macrophages and not from mastocytes.

Authors:  J M Mencia-Huerta; J Benveniste
Journal:  Eur J Immunol       Date:  1979-05       Impact factor: 5.532
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  4 in total

1.  Pharmacologic modulation of experimental postischemic hepatic function.

Authors:  S J Ontell; L Makowka; J Trager; V Mazzaferro; P Ove; T E Starzl
Journal:  Ann Surg       Date:  1989-02       Impact factor: 12.969

2.  Experimental model of ischemic bowel necrosis. The role of platelet-activating factor and endotoxin.

Authors:  F Gonzalez-Crussi; W Hsueh
Journal:  Am J Pathol       Date:  1983-07       Impact factor: 4.307

3.  Platelet activation by endogenous 5-hydroxytryptamine and histamine released by mast cell degranulation with compound 48/80 in the rat.

Authors:  F De Clerck; Y Somers; L Van Gorp; B Xhonneux
Journal:  Agents Actions       Date:  1983-02

Review 4.  Platelets in inflammation: regulation of leukocyte activities and vascular repair.

Authors:  Angèle Gros; Véronique Ollivier; Benoît Ho-Tin-Noé
Journal:  Front Immunol       Date:  2015-01-06       Impact factor: 7.561
  4 in total

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