Literature DB >> 469247

The release of a platelet-activating factor by stimulated rabbit neutrophils.

J M Lynch, G Z Lotner, S J Betz, P M Henson.   

Abstract

Normal rabbit peripheral blood neutrophils released a platelet-activating factor upon stimulation by opsonized zymosan. The liberation was Ca++ dependent and the time course of release was closely associated with phagocytosis. The material extracted into chloroform and exhibited an identical mobility by thin layer chromatography to basophil-derived, IgE-stimulated, platelet-activating factor (PAFb). It was similar to PAFb in its effect on platelets in both aggregation and release but was distinguished from ADP, thrombin, arachidonic acid, and thromboxanes. This factor appears to be responsible for some previously reported neutrophil-platelet interactions.

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Year:  1979        PMID： 469247

Source DB:  PubMed          Journal:  J Immunol        ISSN： 0022-1767            Impact factor:   5.422


  54 in total

1.  Responsiveness of guinea pig alveolar cells.

Authors:  F K Kessler; B J Fisher; D E Bechard; A A Fowler; R A Carchman
Journal:  Lung       Date:  1988       Impact factor: 2.584

2.  Coronary vasoconstriction in the rat, isolated perfused heart induced by platelet-activating factor is mediated by leukotriene C4.

Authors:  P J Piper; A G Stewart
Journal:  Br J Pharmacol       Date:  1986-07       Impact factor: 8.739

3.  Determination of platelet-activating factor by a chemiluminescence method and its application to stimulated guinea pig neutrophils.

Authors:  Y Hasegawa; E Kunow; J Shindou; H Yuki
Journal:  Lipids       Date:  1991-12       Impact factor: 1.880

4.  Effect of platelet-activating factor on secretion of mucous glycoprotein from chinchilla middle ear epithelial cells in vitro.

Authors:  J Lin; Y Kim; C Lees; S K Juhn
Journal:  Eur Arch Otorhinolaryngol       Date:  1995       Impact factor: 2.503

5.  Neutropenia induced by platelet-activating factor (PAF-acether) released from neutrophils: the inhibitory effect of prostacyclin (PGI2).

Authors:  G Camussi; C Tetta; G Segoloni; M Chiara Deregibus; F Bussolino
Journal:  Agents Actions       Date:  1981-12

6.  Indomethacin inhibits the increased airway responsiveness to histamine following inhalation of C5a des Arg in rabbits.

Authors:  N Berend; C L Armour; J L Black
Journal:  Agents Actions       Date:  1986-08

7.  Platelet activating factor: an inhibitor of neutrophil activation?

Authors:  M C O'Donnell; J N Siegel; B A Fiedel
Journal:  Clin Exp Immunol       Date:  1981-01       Impact factor: 4.330

8.  Platelet involvement in rat paw edema induced by 2-methoxy-PAF.

Authors:  P M Silva; R S Cordeiro; M A Martins; M G Henriques; B B Vargaftig
Journal:  Inflammation       Date:  1986-12       Impact factor: 4.092

9.  Enhancement by cyclo-oxygenase inhibitors of platelet-activating factor production in thapsigargin-stimulated macrophages.

Authors:  M Watanabe; M Yamada; S Mue; K Ohuchi
Journal:  Br J Pharmacol       Date:  1995-10       Impact factor: 8.739

10.  Mechanism of action of platelet activating factor in the pulmonary circulation: an investigation using a novel isotopic system in rabbit isolated lung.

Authors:  J P Seale; S Nourshargh; P G Hellewell; T J Williams
Journal:  Br J Pharmacol       Date:  1991-09       Impact factor: 8.739
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