Literature DB >> 7260280

A laser Raman spectroscopic study of Ca2+ binding to troponin C.

E B Carew, P C Leavis, H E Stanley, J Gergely.   

Abstract

Laser Raman spectroscopy has been used detect structural changes in troponin C induced by Ca2+ binding. Addition of Ca2+ - Mg2+ sites produces perturbations in the amide III region of the spectrum indicative of increased alpha-helical content, and in regions of the spectrum corresponding to carboxylate, thiol, and phenol side chains. However, Ca2+ binding to the low affinity Ca2+ - specific sites is not detected by laser Raman spectral changes.

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Year:  1980        PMID: 7260280      PMCID: PMC1328739          DOI: 10.1016/S0006-3495(80)85099-5

Source DB:  PubMed          Journal:  Biophys J        ISSN: 0006-3495            Impact factor:   4.033


  26 in total

1.  Laser Raman spectroscopic studies of ocular lens and its isolated protein fractions.

Authors:  N T Yu; E J East
Journal:  J Biol Chem       Date:  1975-03-25       Impact factor: 5.157

2.  Laser raman spectroscopy--new probe of myosin substructure.

Authors:  E B Carew; I M Asher; H E Stanley
Journal:  Science       Date:  1975-05-30       Impact factor: 47.728

3.  Raman spectroscopic study of tropomyosin denaturation.

Authors:  B G Frushour; J L Koenig
Journal:  Biopolymers       Date:  1974       Impact factor: 2.505

4.  Laser Raman studies of conformational variations of poly-L-lysine.

Authors:  T J Yu; J L Lippert; W L Peticolas
Journal:  Biopolymers       Date:  1973       Impact factor: 2.505

5.  Laser-excited Raman spectroscopy of biomolecules. VI. Some polypeptides as conformational models.

Authors:  M C Chen; R C Lord
Journal:  J Am Chem Soc       Date:  1974-07-24       Impact factor: 15.419

6.  Hydrodynamic and optical properties of troponin A. Demonstration of a conformational change upon binding calcium ion.

Authors:  A C Murray; C M Kay
Journal:  Biochemistry       Date:  1972-07-04       Impact factor: 3.162

7.  Ca ++ induced conformational changes in the Ca ++ binding component of troponin.

Authors:  J P Van Eerd; Y Kawasaki
Journal:  Biochem Biophys Res Commun       Date:  1972-05-26       Impact factor: 3.575

8.  Raman spectra and the phonon dispersion of polyglycine.

Authors:  E W Small; B Fanconi; W L Peticolas
Journal:  J Chem Phys       Date:  1970-05-01       Impact factor: 3.488

9.  Laser-excited Raman spectroscopy of biomolecules. II. Native ribonuclease and alpha-chymotrypsin.

Authors:  R C Lord; N T Yu
Journal:  J Mol Biol       Date:  1970-07-28       Impact factor: 5.469

10.  Laser Raman spectroscopy and the conformation of insulin and proinsulin.

Authors:  N T Yu; C S Liu; D C O'Shea
Journal:  J Mol Biol       Date:  1972-09-14       Impact factor: 5.469

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  3 in total

1.  Quantification of the calcium-induced secondary structural changes in the regulatory domain of troponin-C.

Authors:  S M Gagné; S Tsuda; M X Li; M Chandra; L B Smillie; B D Sykes
Journal:  Protein Sci       Date:  1994-11       Impact factor: 6.725

2.  Studies of myosin and its proteolytic fragments by laser Raman spectroscopy.

Authors:  E B Carew; H E Stanley; J C Seidel; J Gergely
Journal:  Biophys J       Date:  1983-11       Impact factor: 4.033

3.  Tyrosine group behaviour in bovine alpha-lactalbumin as revealed by its Raman effect.

Authors:  H Van Dael; J P Lafaut; F Van Cauwelaert
Journal:  Eur Biophys J       Date:  1987       Impact factor: 1.733

  3 in total

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