| Literature DB >> 7260280 |
E B Carew, P C Leavis, H E Stanley, J Gergely.
Abstract
Laser Raman spectroscopy has been used detect structural changes in troponin C induced by Ca2+ binding. Addition of Ca2+ - Mg2+ sites produces perturbations in the amide III region of the spectrum indicative of increased alpha-helical content, and in regions of the spectrum corresponding to carboxylate, thiol, and phenol side chains. However, Ca2+ binding to the low affinity Ca2+ - specific sites is not detected by laser Raman spectral changes.Entities:
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Year: 1980 PMID: 7260280 PMCID: PMC1328739 DOI: 10.1016/S0006-3495(80)85099-5
Source DB: PubMed Journal: Biophys J ISSN: 0006-3495 Impact factor: 4.033