Literature DB >> 7247975

Effect of cyclophosphamide, hydrocortisone and levamisole on collagen-induced arthritis in rats.

J M Stuart, L K Myers, A S Townes, A H Kang.   

Abstract

The immune response of rats to type II collagen was modified by pretreating the rats with levamisole, hydrocortisone, or cyclophosphamide. Rats were observed for the development of collagen-induced arthritis and were bled serially for the determination of antibody levels to type II collagen. Levamisole had a slight but not significant potentiating effect with arthritis developing earlier, whereas hydrocortisone and cyclophosphamide significantly depressed the incidence of arthritis; cyclophosphamide also delayed its onset. Antibody levels measured by radioimmunoassay paralleled the clinical course of arthritis.

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Year:  1981        PMID： 7247975     DOI： 10.1002/art.1780240606

Source DB:  PubMed          Journal:  Arthritis Rheum        ISSN： 0004-3591


  13 in total

1.  Inhibition by FK506 of established lesions of collagen-induced arthritis in rats.

Authors:  C Arita; T Hotokebuchi; H Miyahara; K Arai; Y Sugioka; N Kaibara
Journal:  Clin Exp Immunol       Date:  1990-12       Impact factor: 4.330

2.  Effects of indomethacin, cyclosporin, cyclophosphamide, and placebo on collagen-induced arthritis of mice.

Authors:  G W Cannon; S McCall; B C Cole; M M Griffiths; L A Radov; J R Ward
Journal:  Agents Actions       Date:  1990-03

3.  Effects of gold sodium thiomalate, cyclosporin A, cyclophosphamide, and placebo on collagen-induced arthritis in rats.

Authors:  G W Cannon; S McCall; B C Cole; L A Radov; J R Ward; M M Griffiths
Journal:  Agents Actions       Date:  1993-03

4.  The influence of a peptide sequence from PF-4 (CT-112) on type II collagen-induced arthritis in mice.

Authors:  P H Wooley; J D Whalen; J A Dutcher; D F Counts
Journal:  Inflamm Res       Date:  1995-08       Impact factor: 4.575

5.  Acceleration of onset of collagen-induced arthritis by intra-articular injection of tumour necrosis factor or transforming growth factor-beta.

Authors:  W O Cooper; R A Fava; C A Gates; M A Cremer; A S Townes
Journal:  Clin Exp Immunol       Date:  1992-08       Impact factor: 4.330

6.  Effect of gold salts, D-penicillamine and benoxaprofen on type II collagen-induced arthritis in rats.

Authors:  A J Lewis; R P Carlson; J Chang; F DeLustro
Journal:  Agents Actions       Date:  1984-06

7.  Assessment of drugs for activity in established type II collagen arthritis.

Authors:  S A Jones; A J Kennedy; N A Roberts
Journal:  Agents Actions       Date:  1982-12

8.  Failure of calcitonin to inhibit collagen-induced arthritis in rats.

Authors:  J M Stuart; P R Bandy; R S Pinals; A S Townes
Journal:  Agents Actions       Date:  1982-12

9.  The influence of superoxide scavenging compound CTC 23 on type II collagen-induced arthritis in mice.

Authors:  P H Wooley; J D Whalen
Journal:  Agents Actions       Date:  1992-03

10.  Nature and specificity of the immune response to collagen in type II collagen-induced arthritis in mice.

Authors:  J M Stuart; A S Townes; A H Kang
Journal:  J Clin Invest       Date:  1982-03       Impact factor: 14.808
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