| Literature DB >> 7246686 |
E Savolainen, E Saksela, L Saxén.
Abstract
During the period 1967-1976, prospectively collected data were available in the Finnish Register of Congenital Malformations on the contraceptive usage of 3,002 mothers of children with malformations detected at birth, as well as of time-matched and place-matched control mothers. The distributions of the various types of malformations were similar among contraceptive users (immediately prior to or during the pregnancy) and nonusers. The total incidences of various methods of contraception were also similar among mothers of malformed children and the control mothers. The risk ratio method for matched pairs allowed us to evaluate the strength of the observed negative correlation concerning oral contraceptives. Thus, we could exclude with 95% confidence any effect larger than 5% of oral contraceptives on the incidence of visible malformations.Entities:
Keywords: Congenital Abnormalities; Contraception; Contraceptive Usage; Control Groups; Demographic Factors; Developed Countries; Diseases; Europe; Family Planning; Fetal Death; Finland; Incidence; Literature Review; Matched Groups; Measurement; Mortality; Neonatal Diseases And Abnormalities; Northern Europe; Oral Contraceptives; Population; Population Dynamics; Prospective Studies; Research Methodology; Scandinavia; Studies
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Year: 1981 PMID： 7246686 DOI： 10.1016/0002-9378(81)90227-1
Source DB: PubMed Journal: Am J Obstet Gynecol ISSN： 0002-9378 Impact factor: 8.661