Literature DB >> 724510

A computer assisted method for the determination of restriction enzyme recognifion sites.

T R Gingeras, J P MIlazzo, R J Roberts.   

Abstract

A computer program has been developed which aids in the determination of restriction enzyme recognition sequences. This is achieved by cleaving DNAs of known sequence with a restriction endonuclease and comparing the fragmentation pattern with a computer-generated set of patterns. The feasibility of this approach has been tested using fragmentation patterns of 0X174 DNA produced by enzymes of both known and unknown specificity. Recognition sequences are predicted for two restriction endonucleases (BbvI and SfaNI) using this method. In addition, recognition sequences are predicted for two other new enzymes (PvuI and MstI) using another computer-assisted method.

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Year:  1978        PMID： 724510      PMCID： PMC342737          DOI： 10.1093/nar/5.11.4105

Source DB:  PubMed          Journal:  Nucleic Acids Res        ISSN： 0305-1048            Impact factor:   16.971


  17 in total

1.  A specific endonuclease from Haemophilus haemolyticus.

Authors:  R J Roberts; P A Myers; A Morrison; K Murray
Journal:  J Mol Biol       Date:  1976-05-05       Impact factor: 5.469

2.  Novel properties of a restriction endonuclease isolated from Haemophilus parahaemolyticus.

Authors:  D Kleid; Z Humayun; A Jeffrey; M Ptashne
Journal:  Proc Natl Acad Sci U S A       Date:  1976-02       Impact factor: 11.205

3.  Nucleotide sequence of bacteriophage phi X174 DNA.

Authors:  F Sanger; G M Air; B G Barrell; N L Brown; A R Coulson; C A Fiddes; C A Hutchison; P M Slocombe; M Smith
Journal:  Nature       Date:  1977-02-24       Impact factor: 49.962

4.  Two sequence-specific endonucleases from Moraxella bovis.

Authors:  R E Gelinas; P A Myers; R J Roberts
Journal:  J Mol Biol       Date:  1977-07       Impact factor: 5.469

5.  Cleavage specificity of the restriction endonuclease isolated from Haemophilus gallinarum (Hga I).

Authors:  N L Brown; M Smith
Journal:  Proc Natl Acad Sci U S A       Date:  1977-08       Impact factor: 11.205

6.  Computer analysis of nucleic acid regulatory sequences.

Authors:  L J Korn; C L Queen; M N Wegman
Journal:  Proc Natl Acad Sci U S A       Date:  1977-10       Impact factor: 11.205

7.  Detection of two restriction endonuclease activities in Haemophilus parainfluenzae using analytical agarose--ethidium bromide electrophoresis.

Authors:  P A Sharp; B Sugden; J Sambrook
Journal:  Biochemistry       Date:  1973-07-31       Impact factor: 3.162

Review 8.  Restriction endonucleases.

Authors:  R J Roberts
Journal:  CRC Crit Rev Biochem       Date:  1976-11

9.  Further procedures for sequence analysis by computer.

Authors:  R Staden
Journal:  Nucleic Acids Res       Date:  1978-03       Impact factor: 16.971

10.  Sequence data handling by computer.

Authors:  R Staden
Journal:  Nucleic Acids Res       Date:  1977-11       Impact factor: 16.971
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  28 in total

1.  The recognition and modification sites for the bacterial type I restriction systems KpnAI, StySEAI, StySENI and StySGI.

Authors:  Julie K A Kasarjian; Masumi Hidaka; Takashi Horiuchi; Masatake Iida; Junichi Ryu
Journal:  Nucleic Acids Res       Date:  2004-06-15       Impact factor: 16.971

2.  Molecular analysis of human argininosuccinate lyase: mutant characterization and alternative splicing of the coding region.

Authors:  D C Walker; D A McCloskey; L R Simard; R R McInnes
Journal:  Proc Natl Acad Sci U S A       Date:  1990-12       Impact factor: 11.205

3.  Directions for clinical research and genomic research into the next decade: implications for informatics.

Authors:  T C Rindfleisch; D L Brutlag
Journal:  J Am Med Inform Assoc       Date:  1998 Sep-Oct       Impact factor: 4.497

4.  Restriction enzymes and their isoschizomers.

Authors:  R J Roberts
Journal:  Nucleic Acids Res       Date:  1990-04-25       Impact factor: 16.971

5.  Restriction enzymes and their isoschizomers.

Authors:  R J Roberts
Journal:  Nucleic Acids Res       Date:  1989       Impact factor: 16.971

6.  Restriction and modification enzymes and their recognition sequences.

Authors:  R J Roberts
Journal:  Nucleic Acids Res       Date:  1985       Impact factor: 16.971

7.  Isolation and computer-aided characterization of MmeI, a type II restriction endonuclease from Methylophilus methylotrophus.

Authors:  A C Boyd; I G Charles; J W Keyte; W J Brammar
Journal:  Nucleic Acids Res       Date:  1986-07-11       Impact factor: 16.971

8.  A putative Type IIS restriction endonuclease GeoICI from Geobacillus sp.--A robust, thermostable alternative to mezophilic prototype BbvI.

Authors:  Joanna Zebrowska; Olga Zolnierkiewicz; Marta A Skowron; Agnieszka Zylicz-Stachula; Joanna Jezewska-Frackowiak; Piotr M Skowron
Journal:  J Biosci       Date:  2016-03       Impact factor: 1.826

9.  Alteration of sequence specificity of the type IIS restriction endonuclease BtsI.

Authors:  Shengxi Guan; Aine Blanchard; Penghua Zhang; Zhenyu Zhu
Journal:  PLoS One       Date:  2010-07-26       Impact factor: 3.240

10.  A putative mobile genetic element carrying a novel type IIF restriction-modification system (PluTI).

Authors:  Feroz Khan; Yoshikazu Furuta; Mikihiko Kawai; Katarzyna H Kaminska; Ken Ishikawa; Janusz M Bujnicki; Ichizo Kobayashi
Journal:  Nucleic Acids Res       Date:  2010-01-13       Impact factor: 16.971
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