Literature DB >> 7241163

Nomifensine: effect in Parkinsonian patients not receiving levodopa.

D M Park, L J Findley, G Hanks, M Sandler.   

Abstract

A clinical trial using the anti-depressant nomifensine in Parkinsonism is reported. Eighteen subjects not receiving levodopa participated. The drug had a small, but significant anti-Parkinsonian effect. No troublesome side effects were encountered. In the treatment of Parkinsonism, nomifensine may be considered as an alternative to amantadine or anticholinergics, especially where depression is an added feature.

Entities:  

Mesh：

Substances：

Year:  1981        PMID： 7241163      PMCID： PMC490961          DOI： 10.1136/jnnp.44.4.352

Source DB:  PubMed          Journal:  J Neurol Neurosurg Psychiatry        ISSN： 0022-3050            Impact factor:   10.154


  9 in total

Review 1.  Recent advances in research on Parkinsonism.

Authors:  U K Rinne
Journal:  Acta Neurol Scand Suppl       Date:  1978

2.  Effect of nomifensine (HOE 984), a new antidepressant, on uptake of noradrenaline and serotonin and on release of noradrenaline in rat brain synaptosomes.

Authors:  U Schacht; W Heptner
Journal:  Biochem Pharmacol       Date:  1974-12-15       Impact factor: 5.858

3.  Nomifensine: a potent dopaminergic agonist of antiparkinson potential.

Authors:  B Costall; D M Kelly; R J Naylor
Journal:  Psychopharmacologia       Date:  1975

4.  Nomifensine: a new potent inhibitor of dopamine uptake into synaptosomes from rat brain corpus striatum.

Authors:  P Hunt; M Kannengiesser; J Raynaud
Journal:  J Pharm Pharmacol       Date:  1974-05       Impact factor: 3.765

5.  Psychiatric symptoms during l-dopa therapy for Parkinson's disease and their relationship to physical disability.

Authors:  R H Mindham; C D Marsden; J D Parkes
Journal:  Psychol Med       Date:  1976-02       Impact factor: 7.723

6.  Nomifensine in parkinsonism.

Authors:  P F Teychenne; D M Park; L J Findley; F C Rose; D B Calne
Journal:  J Neurol Neurosurg Psychiatry       Date:  1976-12       Impact factor: 10.154

7.  Studies on brain metabolism of biogenic amines.

Authors:  U Schacht; M Leven; G Bäcker
Journal:  Br J Clin Pharmacol       Date:  1977       Impact factor: 4.335

8.  Methylphenidate-like effects of the new antidepressant drug nomifensine (HOE 984).

Authors:  C Braestrup; J Scheel-Krüger
Journal:  Eur J Pharmacol       Date:  1976-08       Impact factor: 4.432

9.  Success and problems of long-term levodopa therapy in Parkinson's disease.

Authors:  C D Marsden; J D Parkes
Journal:  Lancet       Date:  1977-02-12       Impact factor: 79.321
  9 in total
  1 in total

Review 1.  Monoamine reuptake inhibitors in Parkinson's disease.

Authors:  Philippe Huot; Susan H Fox; Jonathan M Brotchie
Journal:  Parkinsons Dis       Date:  2015-02-25
  1 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.