Literature DB >> 7235701

Immunosuppression by ochratoxin A and its prevention by phenylalanine.

H D Haubeck, G Lorkowski, E Kölsch, R Röschenthaler.   

Abstract

Ochratoxin A, a toxin of Aspergillus ochraceus, suppresses the immune response to sheep erythrocytes in BALB/c mice at doses as low as 0.005 microgram/kg of body weight. This effect is prevented by phenylalanine.

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Year:  1981        PMID： 7235701      PMCID： PMC243853          DOI： 10.1128/aem.41.4.1040-1042.1981

Source DB:  PubMed          Journal:  Appl Environ Microbiol        ISSN： 0099-2240            Impact factor:   4.792


  10 in total

1.  Induction of autolysis in Bacillus subtilis by ochratoxin A.

Authors:  U Singer; R Röschenthaler
Journal:  Can J Microbiol       Date:  1978-05       Impact factor: 2.419

2.  In vitro inhibition of yeast phenylalanyl-tRNA synthetase by ochratoxin A.

Authors:  E E Creppy; A A Lugnier; F Fasiolo; K Heller; R Röschenthaler; G Dirheimer
Journal:  Chem Biol Interact       Date:  1979-02       Impact factor: 5.192

3.  Interaction of ochratoxin A with bovine serum albumin.

Authors:  F S Chu
Journal:  Arch Biochem Biophys       Date:  1971-12       Impact factor: 4.013

4.  Inhibition of phenylalanine tRNA synthetase from Bacillus subtilis by ochratoxin A.

Authors:  I Konrad; R Röschenthaler
Journal:  FEBS Lett       Date:  1977-11-15       Impact factor: 4.124

5.  In vivo and in vitro inhibition of protein synthesis in Bacillus stearothermophilus by ochratoxin A.

Authors:  I Bunge; G Dirheimer; R Röschenthaler
Journal:  Biochem Biophys Res Commun       Date:  1978-07-28       Impact factor: 3.575

6.  Action of ochratoxin A on cultured hepatoma cells--reversion of inhibition by phenylalanine.

Authors:  E E Creppy; A A Lugnier; G Beck; R Röschenthaler; G Dirheimer
Journal:  FEBS Lett       Date:  1979-08-15       Impact factor: 4.124

7.  [Preventive action of phenylalanine on acute intoxication of ochratoxin-A].

Authors:  E Creppy; M Schlegel; R Röschenthaler; G Dirheimer
Journal:  C R Seances Acad Sci D       Date:  1979-11-19

8.  Ochratoxin A in blood from slaughter pigs in Sweden: use in evaluation of toxin content of consumed feed.

Authors:  K Hult; E Hökby; S Gatenbeck; L Rutqvist
Journal:  Appl Environ Microbiol       Date:  1980-04       Impact factor: 4.792

9.  Ochratoxin A in pig blood: method of analysis and use as a tool for feed studies.

Authors:  K Hult; E Hökby; U Hägglund; S Gatenbeck; L Rutqvist; G Sellyey
Journal:  Appl Environ Microbiol       Date:  1979-11       Impact factor: 4.792

10.  Effect of ochratoxin and aflatoxin on serum proteins, complement activity, and antibody production to Brucella abortus in guinea pigs.

Authors:  J L Richard; J R Thurston; B L Deyoe; G D Booth
Journal:  Appl Microbiol       Date:  1975-01
  10 in total
  16 in total

1.  Detoxification of ochratoxin A, a food contaminant: Prevention of growth of Aspergillus ochraceus and its production of ochratoxin A.

Authors:  P Deberghes; A M Betbeder; F Boisard; R Blanc; J F Delaby; S Krivobok; R Steiman; F Seigle-Murandi; E Creppy
Journal:  Mycotoxin Res       Date:  1995-03       Impact factor: 3.833

2.  Spontaneous occurrence of ochratoxin A residues in porcine kidneys in Belgium.

Authors:  D M Rousseau; C H Van Peteghem
Journal:  Bull Environ Contam Toxicol       Date:  1989-02       Impact factor: 2.151

3.  Ochratoxin A as a suppressor of mitogen-induced blastogenesis of porcine blood lymphocytes.

Authors:  T Holmberg; A Thuvander; K Hult
Journal:  Acta Vet Scand       Date:  1988       Impact factor: 1.695

4.  Inhibition of ochratoxin A production and growth of Aspergillus species by phenolic antioxidant compounds.

Authors:  Jeffrey D Palumbo; Teresa L O'Keeffe; Noreen E Mahoney
Journal:  Mycopathologia       Date:  2007-09-12       Impact factor: 2.574

5.  Sister chromatid exchange frequency in cultured isolated porcine urinary bladder epithelial cells (PUBEC) treated with ochratoxin A and alpha.

Authors:  W Föllmann; I E Hillebrand; E E Creppy; H M Bolt
Journal:  Arch Toxicol       Date:  1995       Impact factor: 5.153

6.  Effects of mycotoxins on the mixed lymphocyte reaction.

Authors:  T Itoh; K Ishii; Y Ueno
Journal:  Mycotoxin Res       Date:  1994-09       Impact factor: 3.833

7.  Foodstuffs and human blood contamination by the mycotoxin ochratoxin A: correlation with chronic interstitial nephropathy in Tunisia.

Authors:  K Maaroufi; A Achour; A M Betbeder; M Hammami; F Ellouz; E E Creppy; H Bacha
Journal:  Arch Toxicol       Date:  1995       Impact factor: 5.153

8.  Effects of two metabolites of ochratoxin A, (4R)-4-hydroxyochratoxin A and ochratoxin alpha, on immune response in mice.

Authors:  E E Creppy; F C Størmer; R Röschenthaler; G Dirheimer
Journal:  Infect Immun       Date:  1983-03       Impact factor: 3.441

9.  Ochratoxin A-induced teratogenesis in rats: partial protection by phenylalanine.

Authors:  K Mayura; R Parker; W O Berndt; T D Phillips
Journal:  Appl Environ Microbiol       Date:  1984-12       Impact factor: 4.792

10.  Distribution of the [3H]-label from low doses of radioactive ochratoxin A ingested by rats, and evidence for DNA single-strand breaks caused in liver and kidneys.

Authors:  A Kane; E E Creppy; A Roth; R Röschenthaler; G Dirheimer
Journal:  Arch Toxicol       Date:  1986-04       Impact factor: 5.153
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