| Literature DB >> 7225552 |
M D Mashkovskiĭ, V Z Gorkin, I V Verevkina, V V Asnina, S M Tupikina.
Abstract
Effect of a new antidepressant pyrazidol (1,10-trimethylene-8-methyl-1,2,3,4-tetrahydropyrazino /1,2-/ indole) on the liver and brain MAO activity of rats was studied in experiments in vivo and in vitro. Pyrazidol selectively blocks type A MAO (the substrates serotonin and noradrenaline) and does not virtually affect or has a far less action on type B MAO (the substrate 2-phenylethylamine).Entities:
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Year: 1981 PMID： 7225552
Source DB: PubMed Journal: Biull Eksp Biol Med ISSN： 0365-9615