Literature DB >> 722122

Ultraviolet light induces epidermal ornithine decarboxylase activity.

M Lowe, A K Verma, R K Boutwell.   

Abstract

Hairless mice were irradiated with fluorescent sun lamp tubes (peak emission at 313 nm). A singificant increase in epidermal ornithine decarboxylase activity was found after 2 hr. A maximum 80-fold increase was found after 24 hr, decreasing again at 48 hr. Epidermal DNA synthesis was decreased at 6 hr and 24 hr increasing to a maximum 48 hr after irradiation. These results show that polyamine biosynthetic enzyme activity precedes the delayed increase in epidermal DNA synthesis following ultraviolet light exposure.

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Year:  1978        PMID： 722122     DOI： 10.1111/1523-1747.ep12558288

Source DB:  PubMed          Journal:  J Invest Dermatol        ISSN： 0022-202X            Impact factor:   8.551


  6 in total

1.  Increased expression of the ornithine decarboxylase gene in mouse skin by ultraviolet light: detection by in situ hybridization technique.

Authors:  M Fukuda; T Kono; M Ishii; N Mizuno; H Tahara; H Yoshida; I Matsui-Yuasa; S Otani; T Hamada
Journal:  Arch Dermatol Res       Date:  1990       Impact factor: 3.017

2.  Increase in the expression of the ornithine decarboxylase gene in mouse skin by ultraviolet light.

Authors:  N Mizuno; T Kono; T Tanii; M Ishii; T Hamada; H Yoshida; I Matsui-Yuasa; S Otani; S Morisawa
Journal:  Arch Dermatol Res       Date:  1989       Impact factor: 3.017

Review 3.  Milestones in photocarcinogenesis.

Authors:  Craig A Elmets; Mohammad Athar
Journal:  J Invest Dermatol       Date:  2013-07-01       Impact factor: 8.551

4.  Photoprotective effects of some quinoxaline 1,4-dioxides in hairless mice.

Authors:  H U Gali-Muhtasib; M J Haddadin; M Z Nazer; N M Sodir; S W Maalouf
Journal:  Med Oncol       Date:  1998-12       Impact factor: 3.064

5.  A novel synthetic vitamin-A-like compound (a polyprenoic acid derivative: E-5166) inhibits UVB-stimulated epidermal ornithine decarboxylase activity.

Authors:  O Nemoto; H Koizumi; T Aoyagi
Journal:  Arch Dermatol Res       Date:  1986       Impact factor: 3.017

6.  Ultraviolet radiation-induced tumor necrosis factor alpha, which is linked to the development of cutaneous SCC, modulates differential epidermal microRNAs expression.

Authors:  Ashok Singh; Estelle Willems; Anupama Singh; Bilal Bin Hafeez; Irene M Ong; Suresh L Mehta; Ajit Kumar Verma
Journal:  Oncotarget       Date:  2016-04-05
  6 in total

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