Literature DB >> 72199

Predicting patients' warfarin requirements.

P A Routledge, D M Davies, S M Bell, J S Cavanagh, M D Rawlins.   

Abstract

In 34 patients undergoing anticoagulant therapy with warfarin a close relationship has been observed between the logarithm of the 'Thrombotest' response to a loading dose (10 mg/day for three days) and the maintenance dose required to achieve an anticoagulant response of 8-12% (thrombo-test). This relationship appears to be close enough to enable maintenance dosages to be predicted.

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Year:  1977        PMID： 72199     DOI： 10.1016/s0140-6736(77)90786-3

Source DB:  PubMed          Journal:  Lancet        ISSN： 0140-6736            Impact factor:   79.321


  13 in total

1.  A simple technique for predicting maintenance dosage of warfarin--is it better than empirical dosing?

Authors:  L Ovesen; S Lyduch; P Ott
Journal:  Eur J Clin Pharmacol       Date:  1989       Impact factor: 2.953

Review 2.  The Smith Kline & French lecture 1987. Clinical pharmacology and the art of bespoke prescribing.

Authors:  P A Routledge
Journal:  Br J Clin Pharmacol       Date:  1988-10       Impact factor: 4.335

3.  Control of warfarin therapy.

Authors:  A Fennerty; P A Routledge
Journal:  Postgrad Med J       Date:  1990-02       Impact factor: 2.401

4.  Dosage individualization of warfarin using artificial neural networks.

Authors:  Mohammad I Saleh; Sameh Alzubiedi
Journal:  Mol Diagn Ther       Date:  2014-06       Impact factor: 4.074

5.  Initiation of warfarin therapy: comparison of physician dosing with computer-assisted dosing.

Authors:  R H White; R Hong; A P Venook; M M Daschbach; W Murray; D R Mungall; R W Coleman
Journal:  J Gen Intern Med       Date:  1987 May-Jun       Impact factor: 5.128

6.  Monitoring effects of oral anticoagulants during treatment with heparin.

Authors:  P Thomas; A Fennerty; G Backhouse; D P Bentley; I A Campbell; P A Routledge
Journal:  Br Med J (Clin Res Ed)       Date:  1984-01-21

7.  A model which predicts maintenance warfarin dosage requirements from the response to a single dose.

Authors:  G M Peterson; S McLean; D M Jupe; R L Griffith; J R Roberts
Journal:  Br J Clin Pharmacol       Date:  1985-08       Impact factor: 4.335

8.  Flexible induction dose regimen for warfarin and prediction of maintenance dose.

Authors:  A Fennerty; J Dolben; P Thomas; G Backhouse; D P Bentley; I A Campbell; P A Routledge
Journal:  Br Med J (Clin Res Ed)       Date:  1984-04-28

9.  Warfarin dosage requirements: prospective clinical trial of a method for prediction from the response to a single dose.

Authors:  D M Jupe; G M Peterson; R L Coleman; S McLean
Journal:  Br J Clin Pharmacol       Date:  1988-05       Impact factor: 4.335

Review 10.  Clinical pharmacokinetics and pharmacodynamics of warfarin. Understanding the dose-effect relationship.

Authors:  N H Holford
Journal:  Clin Pharmacokinet       Date:  1986 Nov-Dec       Impact factor: 6.447
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