Literature DB >> 7213803

Structural analysis of human hemoglobin variants with field desorption mass spectrometry.

Y Wada, A Hayashi, T Fujita, T Matsuo, I Katakuse, H Matsuda.   

Abstract

Tryptic hydrolyzates of normal and abnormal human globin chains were analyzed with mass spectrometry, using field desorption ionization technique. All the peptides, including core peptides, were detected as protonated molecular ions in field desorption mass spectra. Since the technique makes it possible to determine the mass number of each peptide, it is very useful for structural analysis of human hemoglobin variants, even those with electrophoretically and chromatographically silent mutations.

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Year:  1981        PMID： 7213803     DOI： 10.1016/0005-2795(81)90188-4

Source DB:  PubMed          Journal:  Biochim Biophys Acta        ISSN： 0006-3002


  7 in total

1.  Characterization of the elusive disulfide bridge forming human Hb variant: Hb Ta-Li beta83 (EF7)Gly --> Cys by electrospray mass spectrometry.

Authors:  Dilip K Rai; Britta Landin; William J Griffiths; Gunvor Alvelius; Brian N Green
Journal:  J Am Soc Mass Spectrom       Date:  2002-02       Impact factor: 3.109

2.  Determination of unique amino acid substitutions in protein variants by peptide mass mapping with FT-ICR MS.

Authors:  Katsuhiro Tanaka; Shigeo Takenaka; Shingo Tsuyama; Yoshinao Wada
Journal:  J Am Soc Mass Spectrom       Date:  2006-02-20       Impact factor: 3.109

3.  Electrospray ionization-tandem mass spectrometry analysis of peptides derived by enzymatic digestion of oxidized globin subunits: An improved method to determine amino acid substitution in the hemoglobin "core".

Authors:  T Nakanishi; A Miyazaki; M Kishikawa; A Shimizu; T Yonezawa
Journal:  J Am Soc Mass Spectrom       Date:  1996-10       Impact factor: 3.109

4.  MALDI-ISD Mass Spectrometry Analysis of Hemoglobin Variants: a Top-Down Approach to the Characterization of Hemoglobinopathies.

Authors:  Roger Théberge; Sergei Dikler; Christian Heckendorf; David H K Chui; Catherine E Costello; Mark E McComb
Journal:  J Am Soc Mass Spectrom       Date:  2015-05-22       Impact factor: 3.109

5.  Using surface-assisted laser desorption/ionization mass spectrometry to detect ss- and ds-oligodeoxynucleotides.

Authors:  Wen-Tsen Chen; Ming-Feng Huang; Huan-Tsung Chang
Journal:  J Am Soc Mass Spectrom       Date:  2013-03-29       Impact factor: 3.109

6.  Fast-atom-bombardment mass spectrometry. A new technique for the determination of molecular weights and amino acid sequences of peptides.

Authors:  D H Williams; C V Bradley; S Santikarn; G Bojesen
Journal:  Biochem J       Date:  1982-01-01       Impact factor: 3.857

7.  Ion trap collision-induced dissociation of human hemoglobin alpha-chain cations.

Authors:  Tegafaw T Mekecha; Ravi Amunugama; Scott A McLuckey
Journal:  J Am Soc Mass Spectrom       Date:  2006-05-15       Impact factor: 3.109
  7 in total

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