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Literature DB >> 7213266

Long-term follow-up of Skylab bone demineralization.

F E Tilton, J J Degioanni, V S Schneider.

Abstract

The os calcis mineral was measured in the nine Skylab crew members and in eight control subjects, 5 years after the Skylab Program, utilizing a photon absorptiometric technique. These measurements were compared with preflight measurements in an attempt to discover any long-term effects of space flight on the skeletal system. A statistically significant loss of bone mineral was found in the crew members who flew, but caution is urged in the interpretation of this difference. A recommendation to continue studies of this type is made.

Mesh：

Year: 1980 PMID： 7213266

Source DB: PubMed Journal: Aviat Space Environ Med ISSN： 0095-6562

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Cited

20 in total

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Authors: Shane A Lloyd; Sean E Morony; Virginia L Ferguson; Steven J Simske; Louis S Stodieck; Kelly S Warmington; Eric W Livingston; David L Lacey; Paul J Kostenuik; Ted A Bateman
Journal: Bone Date: 2015-08-28 Impact factor: 4.398

2. Long-term dose response of trabecular bone in mice to proton radiation.

Authors: Eric R Bandstra; Michael J Pecaut; Erica R Anderson; Jeffrey S Willey; Francesco De Carlo; Stuart R Stock; Daila S Gridley; Gregory A Nelson; Howard G Levine; Ted A Bateman
Journal: Radiat Res Date: 2008-06 Impact factor: 2.841

3. A systematic review and meta-analysis of bone loss in space travelers.

Authors: Mariya Stavnichuk; Nicholas Mikolajewicz; Tatsuya Corlett; Martin Morris; Svetlana V Komarova
Journal: NPJ Microgravity Date: 2020-05-05 Impact factor: 4.415

4. Lactating Ctcgrp nulls lose twice the normal bone mineral content due to fewer osteoblasts and more osteoclasts, whereas bone mass is fully restored after weaning in association with up-regulation of Wnt signaling and other novel genes.

Authors: Jillian N Collins; Beth J Kirby; Janine P Woodrow; Robert F Gagel; Clifford J Rosen; Natalie A Sims; Christopher S Kovacs
Journal: Endocrinology Date: 2013-03-05 Impact factor: 4.736

Long-term follow-up of Skylab bone demineralization.

1. Osteoprotegerin is an effective countermeasure for spaceflight-induced bone loss in mice.

2. Long-term dose response of trabecular bone in mice to proton radiation.

3. A systematic review and meta-analysis of bone loss in space travelers.

4. Lactating Ctcgrp nulls lose twice the normal bone mineral content due to fewer osteoblasts and more osteoclasts, whereas bone mass is fully restored after weaning in association with up-regulation of Wnt signaling and other novel genes.

5. Functional strain as a determinant for bone remodeling.

6. Fifteen days of microgravity causes growth in calvaria of mice.

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8. A reproducible radiation delivery method for unanesthetized rodents during periods of hind limb unloading.

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10. Oxidative stress and gamma radiation-induced cancellous bone loss with musculoskeletal disuse.