Literature DB >> 721135

Studies on the control of antibody synthesis. XII. Genetic influences on antibody affinity.

Y T Kim, G W Siskind.   

Abstract

Genetic controls on the concentration and affinity of the anti-dinitrophenyl antibodies produced by different inbred strains of mice in response to immunization with dinitrophenylated bovine gamma globulin in Freund's complete adjuvant were demonstrated. Based upon data on F1 hybrids and backcrosses, it can be concluded that there are genetic controls on antibody affinity which are not linked to the major histocompatibility complex. In addition, the genetic controls on affinity which were studied here appear to be inherited independently of genetic controls on antibody concentration.

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Year:  1978        PMID： 721135      PMCID： PMC1457184     

Source DB:  PubMed          Journal:  Immunology        ISSN： 0019-2805            Impact factor:   7.397


  20 in total

1.  VARIATIONS IN AFFINITIES OF ANTIBODIES DURING THE IMMUNE RESPONSE.

Authors:  H N EISEN; G W SISKIND
Journal:  Biochemistry       Date:  1964-07       Impact factor: 3.162

2.  Effect of tolerance and immunity on antibody affinity.

Authors:  T P Werblin; G W Siskind
Journal:  Transplant Rev       Date:  1972

3.  Distribution of antibody affinities: technique of measurement.

Authors:  T P Werblin; G W Siskind
Journal:  Immunochemistry       Date:  1972-10

Review 4.  Histocompatibility-linked immune response genes.

Authors:  B Benacerraf; H O McDevitt
Journal:  Science       Date:  1972-01-21       Impact factor: 47.728

5.  Rate of increase of antibody affinity in different rat strains.

Authors:  J P Lamelin; W E Paul
Journal:  Int Arch Allergy Appl Immunol       Date:  1971

6.  The genetic control of antibody binding constants and specificities in inbred rats.

Authors:  S K Ruscetti; H W Kunz; T J Gill
Journal:  J Immunol       Date:  1974-11       Impact factor: 5.422

7.  Studies on the genetic control of antibody affinity: the independent control of antibody levels and affinity in Biozzi mice.

Authors:  F E Katz; M W Steward
Journal:  J Immunol       Date:  1976-08       Impact factor: 5.422

8.  Purification of antibodies with immunoadsorbents prepared using bromoacetyl cellulose.

Authors:  J B Robbins; J Haimovich; M Sela
Journal:  Immunochemistry       Date:  1967-01

9.  Studies on the control of antibody synthesis. VII. Change in affinity of direct and indirect plaque-forming cells with time after immunization in the mouse: loss of high affinity plaques late after immunization.

Authors:  E A Goidl; J J Barondess; G W Siskind
Journal:  Immunology       Date:  1975-10       Impact factor: 7.397

10.  Inheritance of antibody specificity. I. Anti-(4-hydroxy-3-nitrophenyl)acetyl of the mouse primary response.

Authors:  T Imanishi; O Mäkelä
Journal:  J Exp Med       Date:  1974-12-01       Impact factor: 14.307
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  11 in total

1.  Chronic immune complex disease in mice: the role of antibody affinity.

Authors:  M W Steward
Journal:  Clin Exp Immunol       Date:  1979-12       Impact factor: 4.330

Review 2.  Antibody affinity: immunogenetic aspects and relationship to immune complex disease.

Authors:  M W Steward
Journal:  J Clin Pathol Suppl (R Coll Pathol)       Date:  1979

3.  Estimating duration of infection with avidity assays: potential limitations and recommendations for improvement.

Authors:  Johanna Varner; M Denise Dearing
Journal:  Ecohealth       Date:  2012-02-07       Impact factor: 3.184

4.  The genetic control of antibody affinity. Evidence from breeding studies with mice selectively bred for either high or low affinity antibody production.

Authors:  M W Steward; M C Reinhardt; N A Staines
Journal:  Immunology       Date:  1979-07       Impact factor: 7.397

5.  Genetic control of igG2a production in the response to sheep erythrocytes.

Authors:  M Seman; V Zilberfarb; M Stanislawski; J M Dubert
Journal:  Immunogenetics       Date:  1978-12       Impact factor: 2.846

6.  Enhanced IgG1 and IgG3 responses to pneumococcal polysaccharides in isolated IgA deficiency.

Authors:  D M Roberton; J Björkander; J Henrichsen; T Söderström; L A Hanson
Journal:  Clin Exp Immunol       Date:  1989-02       Impact factor: 4.330

7.  Antibody avidity in swine lymphocyte antigen-defined miniature pigs.

Authors:  G D Appleyard; B A Mallard; B W Kennedy; B N Wilkie
Journal:  Can J Vet Res       Date:  1992-10       Impact factor: 1.310

8.  The induction of chronic antigen-antibody complex disease in selectively bred mice producing either high or low affinity antibody to protein antigens.

Authors:  M E Devey; M W Steward
Journal:  Immunology       Date:  1980-10       Impact factor: 7.397

9.  Synthetic peptide vaccine targeting a cryptic neutralizing epitope in domain 2 of Bacillus anthracis protective antigen.

Authors:  Jon Oscherwitz; Fen Yu; Jana L Jacobs; Te-Hui Liu; Philip R Johnson; Kemp B Cease
Journal:  Infect Immun       Date:  2009-06-01       Impact factor: 3.441

10.  Comparison of concentration and avidity of specific antibodies to E. coli in breast milk and serum.

Authors:  F H Sennhauser; R A Macdonald; D M Roberton; C S Hosking
Journal:  Immunology       Date:  1989-03       Impact factor: 7.397
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