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Literature DB >> 720783

Growth hormone enhances basement membrane thickening in experimental diabetes. A preliminary report.

R Osterby, K Seyer-Hansen, H J Gundersen, K Lundbaek.

Abstract

Injection of porcine growth hormone (200 microgram) or saline 5 days a week for 16 to 20 weeks in streptozotocin-diabetic rats showed that compared to saline growth hormone produced a 2 1/2-fold larger increase in glomerular capillary basement membrane thickness (2p = 0.027). The possible significance of this effect of an elevated level of growth hormone for diabetic microangiopathy is discussed.

Entities: Chemical Disease Gene Species

Mesh：

Substances：
Growth Hormone

Year: 1978 PMID： 720783 DOI： 10.1007/bf02342875

Source DB: PubMed Journal: Diabetologia ISSN： 0012-186X Impact factor: 10.122

6 in total

1. Serum growth hormone patterns in juvenile diabetes.

Authors: A P Hansen
Journal: Dan Med Bull Date: 1972-04

2. Determination of membrane thickness distribution from orthogonal intercepts.

Authors: E B Jensen; H J Gundersen; R Osterby
Journal: J Microsc Date: 1979-01 Impact factor: 1.758

Review 3. The pathogenesis of diabetic angiopathy and growth hormone.

Authors: K Lundbaek; N J Christensen; V A Jensen; K Johansen; T S Olsen; A P Hansen; H Orskov; R Osterby
Journal: Dan Med Bull Date: 1971-02

4. Diabetes, diabetic angiopathy, and growth hormone.

Authors: K Lundbaek; N J Christensen; V A Jensen; K Johansen; T S Olsen; A P Hansen; H Orskov; R Osterby
Journal: Lancet Date: 1970-07-18 Impact factor: 79.321

Review 5. Search for a biochemical basis of diabetic microangiopathy.

Authors: R G Spiro
Journal: Diabetologia Date: 1976-03 Impact factor: 10.122

6. Prevention of diabetic glomerulopathy in streptozotocin diabetic rats by insulin treatment. Kidney size and glomerular volume.

Authors: R Rasch
Journal: Diabetologia Date: 1979-02 Impact factor: 10.122

6 in total

11 in total

1. Diabetic cardiopathy.

Authors: T Ledet; B Neubauer; N J Christensen; K Lundbaek
Journal: Diabetologia Date: 1979-04 Impact factor: 10.122

2. Wake and sleep cardiovascular reflex tests and GH profiles in diabetic patients.

Authors: R Silvestri; A Lasco; L Marabello; R M Puglisi; C Casella; D Cucinotta; O Manganaro; N Frisina; R Di Perri
Journal: Acta Diabetol Lat Date: 1989 Jul-Sep

3. Effect of aging on growth hormone, ACTH and cortisol response to insulin-induced hypoglycemia in type I diabetes.

Authors: M Muggeo; P Moghetti; M Querena; S Girotto; E Bonora; G Crepaldi
Journal: Acta Diabetol Lat Date: 1985 Apr-Jun

4. Are the 'second generation' oral hypoglycemic agents really different?

Authors: E F Pfeiffer
Journal: Acta Diabetol Lat Date: 1984 Jan-Mar

5. Acute renal hypertrophy in experimental diabetes: lack of effect of short-term growth hormone administration.

Authors: K Seyer-Hansen; H J Gundersen; R Osterby
Journal: Diabetologia Date: 1981-10 Impact factor: 10.122

6. Absence of muscle capillary basement membrane thickening and retinopathy in patients with myocardial infarction and impaired i.v. glucose tolerance.

Authors: H J Quabbe; K E Schenk; H Schneider; M Semrau; G Hövener
Journal: Acta Diabetol Lat Date: 1983 Oct-Dec

Review 10. The natural history of diabetic nephropathy in type I diabetes and the role of metabolic control in its prevention, reversibility and clinical course.

Authors: B L Wajchenberg; E Sabbaga; J A Fonseca
Journal: Acta Diabetol Lat Date: 1983 Jan-Mar