Literature DB >> 7205247

Effect of choline on central dopaminergic function in normal subjects.

S Lal, P Etienne, J Thavundayil, N P Nair, B Collier, R Rastogi, H Guyda, G Schwartz.   

Abstract

Oral administration of choline (10 g) had no effect on basal serum growth hormone or prolactin concentrations in normal subjects (N = 5). Choline significantly enhanced the increase in growth hormone secretion induced by apomorphine HCl (0.5 mg s.c.). These data suggest that cholinergic mechanisms may enhance hypothalamic-pituitary dopaminergic function in man in contrast to their inhibitory effect on dopaminergic function in the basal ganglia.

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Year:  1981        PMID: 7205247     DOI: 10.1007/bf01254911

Source DB:  PubMed          Journal:  J Neural Transm            Impact factor:   3.575


  24 in total

1.  Comparison of the effect of apomorphine and L-DOPA on serum growth hormone levels in normal men.

Authors:  S Lal; J B Martin; C E De la Vega; H G Friesen
Journal:  Clin Endocrinol (Oxf)       Date:  1975-05       Impact factor: 3.478

2.  Choline in tardive dyskinesia and Huntington's disease.

Authors:  K L Davis; L E Hollister; J D Barchas; P A Berger
Journal:  Life Sci       Date:  1976-11-15       Impact factor: 5.037

3.  Oral choline administration to patients with tardive dyskinesia.

Authors:  J H Growdon; M J Hirsch; R J Wurtman; W Wiener
Journal:  N Engl J Med       Date:  1977-09-08       Impact factor: 91.245

4.  Effect of apomorphine on human-growth-hormone secretion.

Authors:  S Lal; C E De la Vega; T L Sourkes; H G Friesen
Journal:  Lancet       Date:  1972-09-23       Impact factor: 79.321

5.  Inhibition by apomorphine of prolactin secretion in patients with elevated serum prolactin.

Authors:  J B Martin; S Lal; G Tolis; H G Friesen
Journal:  J Clin Endocrinol Metab       Date:  1974-07       Impact factor: 5.958

6.  Choline chloride in methylphenidate- and apomorphine-induced stereotypy.

Authors:  K L Davis; L E Hollister; A L Vento; S Simonton
Journal:  Life Sci       Date:  1978-06-26       Impact factor: 5.037

7.  Influence of choline on amnesia in early Alzheimer's disease.

Authors:  J L Signoret; A Whiteley; F Lhermitte
Journal:  Lancet       Date:  1978-10-14       Impact factor: 79.321

8.  Metoclopramide stimulates prolactin secretion in man.

Authors:  R W McCallum; J R Sowers; J M Hershman; R A Sturdevant
Journal:  J Clin Endocrinol Metab       Date:  1976-06       Impact factor: 5.958

9.  Effect of clozapine on apomorphine-induced growth hormone secretion and serum prolactin concentrations in schizophrenia.

Authors:  N P Nair; S Lal; P Cervantes; R Yassa; H Guyda
Journal:  Neuropsychobiology       Date:  1979       Impact factor: 2.328

10.  Choline excites cortical neurons.

Authors:  K Krnjević; W Reinhardt
Journal:  Science       Date:  1979-12-14       Impact factor: 47.728

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  2 in total

1.  Hypothalamic-pituitary dopaminergic function in hepatic failure in man.

Authors:  S Lal; M Oravec; A Aronoff; M E Kiely; H Guyda; S Solomon; N P Nair
Journal:  J Neural Transm       Date:  1982       Impact factor: 3.575

2.  Effect of domperidone on apomorphine-induced growth hormone secretion in normal men.

Authors:  S Lal; N P Nair; H L Iskandar; P Etienne; P L Wood; G Schwartz; H Guyda
Journal:  J Neural Transm       Date:  1982       Impact factor: 3.575

  2 in total

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