Literature DB >> 7204562

Human platelet stimulation by acetyl glyceryl ether phosphorylcholine.

L M McManus, D J Hanahan, R N Pinckard.   

Abstract

Acetyl glyceryl ether phosphorylcholine (AGEPC) induced dose-dependent platelet aggregation and release of [3H]serotonin and platelet factor 4 in citrated human platelet-rich plasma. ADP scavengers or indomethacin prevented irreversible platelet aggregation responses induced by 0.2 microM AGEPC but had no effect upon platelet secretion; prostacyclin inhibited AGEPC-induced aggregation and secretion. EDTA or EGTA inhibited AGEPC-induced aggregation but had no effect on platelet secretion.

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Year:  1981        PMID： 7204562      PMCID： PMC370642          DOI： 10.1172/jci110108

Source DB:  PubMed          Journal:  J Clin Invest        ISSN： 0021-9738            Impact factor:   14.808


  22 in total

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Journal:  Monogr Allergy       Date:  1977

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Journal:  Nature       Date:  1974-06-07       Impact factor: 49.962

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Authors:  J Benveniste; J P Le Couedic; P Kamoun
Journal:  Lancet       Date:  1975-02-08       Impact factor: 79.321

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Authors:  M C O'Donnell; P M Henson; B A Fiedel
Journal:  Immunology       Date:  1978-12       Impact factor: 7.397

Review 7.  Platelet activating factor (PAF). A possible direct mediator of anaphylaxis in the rabbit and a trigger for the vascular deposition of circulating immune complexes.

Authors:  P M Henson; R N Pinckard
Journal:  Monogr Allergy       Date:  1977

8.  The release of four mediators of immediate hypersensitivity from human leukemic basophils.

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Journal:  J Immunol       Date:  1975-01       Impact factor: 5.422

9.  Mediator release from basophil granulocytes in chronic myelogenous leukemia.

Authors:  R A Clark; J I Gallin; A P Kaplan
Journal:  J Allergy Clin Immunol       Date:  1976-12       Impact factor: 10.793

10.  Release of vasoactive amines from rabbit platelets induced by sensitized mononuclear leukocytes and antigen.

Authors:  P M Henson
Journal:  J Exp Med       Date:  1970-02       Impact factor: 14.307
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  31 in total

1.  Effects of the PAF antagonists BN50726 and BN50739 on arrhythmogenesis and extent of necrosis during myocardial ischaemia/reperfusion in rabbits.

Authors:  S Chakrabarty; D S Fluck; N A Flores; D J Sheridan
Journal:  Br J Pharmacol       Date:  1992-11       Impact factor: 8.739

2.  Electrophysiological and arrhythmogenic effects of platelet activating factor during normal perfusion, myocardial ischaemia and reperfusion in the guinea-pig.

Authors:  N A Flores; D J Sheridan
Journal:  Br J Pharmacol       Date:  1990-11       Impact factor: 8.739

3.  Interruption of acute platelet-dependent thrombosis by the synthetic antithrombin D-phenylalanyl-L-prolyl-L-arginyl chloromethyl ketone.

Authors:  S R Hanson; L A Harker
Journal:  Proc Natl Acad Sci U S A       Date:  1988-05       Impact factor: 11.205

Review 4.  Platelet activating factor in heart failure: potential role in disease progression and novel target for therapy.

Authors:  Paraskevi Detopoulou; Tzortzis Nomikos; Elizabeth Fragopoulou; Christina Chrysohoou; Smaragdi Antonopoulou
Journal:  Curr Heart Fail Rep       Date:  2013-06

5.  Stimulus-response coupling in human platelets. Changes evoked by platelet-activating factor in cytoplasmic free calcium monitored with the fluorescent calcium indicator quin2.

Authors:  T J Hallam; A Sanchez; T J Rink
Journal:  Biochem J       Date:  1984-03-15       Impact factor: 3.857

6.  Triggering by Paf-acether and adrenaline of cyclo-oxygenase-independent platelet aggregation.

Authors:  F Fouque; B B Vargaftig
Journal:  Br J Pharmacol       Date:  1984-11       Impact factor: 8.739

7.  Studies on the role of platelet-activating factor in blood pressure regulation.

Authors:  K Sakaguchi; S Morimoto; F Masugi; S Saeki; T Ogihara; K Yamada; I Yamatsu
Journal:  Lipids       Date:  1991-12       Impact factor: 1.880

8.  Enhancement by cyclo-oxygenase inhibitors of platelet-activating factor production in thapsigargin-stimulated macrophages.

Authors:  M Watanabe; M Yamada; S Mue; K Ohuchi
Journal:  Br J Pharmacol       Date:  1995-10       Impact factor: 8.739

9.  Isolation of a platelet membrane protein which binds the platelet-activating factor 1-0-hexadecyl-2-acetyl-SN-glycero-3-phosphorylcholine.

Authors:  F H Valone
Journal:  Immunology       Date:  1984-05       Impact factor: 7.397

10.  Acetyl glyceryl ether phosphorylcholine stimulates leukotriene B4 synthesis in human polymorphonuclear leukocytes.

Authors:  A H Lin; D R Morton; R R Gorman
Journal:  J Clin Invest       Date:  1982-11       Impact factor: 14.808
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