| Literature DB >> 7203467 |
Abstract
The influence of temperature on sister chromatid exchanges was investigated, and the results are discussed in connection with factors possible involved in temperature-induced SCE-formation. Whereas the SCE frequency increased with increasing growth temperature in a cell line of Xenopus laevis (EAX), which permits the examination of great temperature differences, a Chinese hamster cell line (V-79) revealed a U-shaped temperature-response curve. In addition, it was found that cold treatment at 4 degrees C caused an induction of SCEs in the V-79 cell line. Different BrdU concentrations had no effect on the temperature-induced SCE frequencies and mitomycin C led to an induction of SCEs parallel to the base-line values at different temperatures.Entities:
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Year: 1980 PMID: 7203467 DOI: 10.1007/bf00290213
Source DB: PubMed Journal: Hum Genet ISSN: 0340-6717 Impact factor: 4.132