Literature DB >> 7199757

Tumor imaging with radioactive metal chelates conjugated to monoclonal antibodies.

D A Scheinberg, M Strand, O A Gansow.   

Abstract

High-resolution gamma camera images of mouse erythroid tumors were obtained by use of leukemia cell-specific monoclonal antibodies labeled with bifunctional radioactive metal chelates. Small tumors (200 to 300 milligrams) were visible without subtraction or enhancement 1 to 5 hours after injection of antibody. Chelate-derivitized monoclonal antibodies permit targeting of a broad spectrum of radioisotopes, including those that are optimum for agamma for gamma camera imaging or positron tomography, as well as those that are tumoricidal.

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Year:  1982        PMID： 7199757     DOI： 10.1126/science.7199757

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  31 in total

1.  New lyophilized kit for rapid radiofluorination of peptides.

Authors:  William J McBride; Christopher A D'Souza; Habibe Karacay; Robert M Sharkey; David M Goldenberg
Journal:  Bioconjug Chem       Date:  2012-02-10       Impact factor: 4.774

Review 2.  Conscripts of the infinite armada: systemic cancer therapy using nanomaterials.

Authors:  David A Scheinberg; Carlos H Villa; Freddy E Escorcia; Michael R McDevitt
Journal:  Nat Rev Clin Oncol       Date:  2010-03-30       Impact factor: 66.675

3.  Antibody Conjugate Assembly on Ultrasound-Confined Microcarrier Particles.

Authors:  Michael M Binkley; Mingyang Cui; Mikhail Y Berezin; J Mark Meacham
Journal:  ACS Biomater Sci Eng       Date:  2020-10-09

4.  Bismuth-212-labeled anti-Tac monoclonal antibody: alpha-particle-emitting radionuclides as modalities for radioimmunotherapy.

Authors:  R W Kozak; R W Atcher; O A Gansow; A M Friedman; J J Hines; T A Waldmann
Journal:  Proc Natl Acad Sci U S A       Date:  1986-01       Impact factor: 11.205

Review 5.  Approaches to radiolabeling of antibodies for diagnosis and therapy of cancer.

Authors:  A R Fritzberg; R W Berninger; S W Hadley; D W Wester
Journal:  Pharm Res       Date:  1988-06       Impact factor: 4.200

6.  Improved 18F labeling of peptides with a fluoride-aluminum-chelate complex.

Authors:  William J McBride; Christopher A D'Souza; Robert M Sharkey; Habibe Karacay; Edmund A Rossi; Chien-Hsing Chang; David M Goldenberg
Journal:  Bioconjug Chem       Date:  2010-07-21       Impact factor: 4.774

7.  Use of monoclonal antibodies and liposomes to improve drug delivery. Present status and future implications.

Authors:  G Gregoriadis
Journal:  Drugs       Date:  1982-10       Impact factor: 9.546

8.  Specific and stable labeling of antibodies with technetium-99m with a diamide dithiolate chelating agent.

Authors:  A R Fritzberg; P G Abrams; P L Beaumier; S Kasina; A C Morgan; T N Rao; J M Reno; J A Sanderson; A Srinivasan; D S Wilbur
Journal:  Proc Natl Acad Sci U S A       Date:  1988-06       Impact factor: 11.205

9.  Human parathyroid antigen: characterization and localization with monoclonal antibodies.

Authors:  W G Cance; S A Wells; W G Dilley; M J Welch; F L Otsuka; J M Davie
Journal:  Proc Natl Acad Sci U S A       Date:  1986-08       Impact factor: 11.205

10.  Site-related differences in the localization of the monoclonal antibody OX7 in SL2 and SL1 lymphomas.

Authors:  H Sands; P L Jones; W P Neacy; S A Shah; B M Gallagher
Journal:  Cancer Immunol Immunother       Date:  1986       Impact factor: 6.968
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